Homo sapiens Gene: ZPBP
Summary
InnateDB Gene IDBG-16327.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZPBP
Gene Name zona pellucida binding protein
Synonyms ZPBP1;
Species Homo sapiens
Ensembl Gene ENSG00000042813
Encoded Proteins
zona pellucida binding protein
zona pellucida binding protein
zona pellucida binding protein
zona pellucida binding protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary ZPBP is one of several proteins that are thought to participate in secondary binding between acrosome-reacted sperm and the egg-specific extracellular matrix, the zona pellucida (McLeskey et al., 1998 [PubMed 9378618]).[supplied by OMIM, Aug 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:49850421-50121329
Strand Reverse strand
Band p12.2
Transcripts
ENST00000046087 ENSP00000046087
ENST00000419417 ENSP00000402071
ENST00000450231 ENSP00000390054
ENST00000413331 ENSP00000414755
ENST00000491129
ENST00000465922
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0001675 acrosome assembly
GO:0007339 binding of sperm to zona pellucida
Cellular Component
GO:0001669 acrosomal vesicle
GO:0002199 zona pellucida receptor complex
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0044297 cell body
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.388841 Hs.606870 Hs.730437
RefSeq NM_001159878 NM_007009
HUGO
OMIM
CCDS CCDS5509 CCDS55110
HPRD 18364
IMGT
EMBL
GenPept
RNA Seq Atlas