Version 5.4
Mus musculus Gene: Wdr4
Summary
InnateDB Gene IDBG-164363.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Wdr4
Gene Name WD repeat domain 4
Synonyms AI415180; AI448349; D530049K22Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000024037
Encoded Proteins
IDBP-625975
WD repeat domain 4
IDBP-625978
WD repeat domain 4
IDBP-625980
WD repeat domain 4
IDBP-625982
WD repeat domain 4
IDBP-625983
WD repeat domain 4
IDBP-625984
WD repeat domain 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000160193:
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is excluded as a candidate for a form of nonsyndromic deafness (DFNB10), but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:31494323-31519974
Strand Reverse strand
Band B1
Transcripts
ENSMUST00000171171 ENSMUSP00000126061
ENSMUST00000172284 ENSMUSP00000129736
ENSMUST00000170176 ENSMUSP00000127073
ENSMUST00000169454
ENSMUST00000166992
ENSMUST00000169224
ENSMUST00000171291 ENSMUSP00000132290
ENSMUST00000167419 ENSMUSP00000127617
ENSMUST00000166626 ENSMUSP00000125954
ENSMUST00000171592
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008176 tRNA (guanine-N7-)-methyltransferase activity
Biological Process
GO:0006400 tRNA modification
GO:0030488 tRNA methylation
GO:0036265 RNA (guanine-N7)-methylation
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000160193
View Gene Order
ENSBTAG00000021490
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.143771 Mm.412316 Mm.489455
RefSeq NM_021322 XM_006524715 XM_006524716 XM_006524717 XM_006524718 XM_006524721 XM_006524722 XM_006524723 XM_006524724 XM_006524725
OMIM
CCDS CCDS28606
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca