Version 5.4
Mus musculus Gene: Prmt2
Summary
InnateDB Gene IDBG-164625.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Prmt2
Gene Name protein arginine N-methyltransferase 2
Synonyms AI504737; Hrmt1l1
Species Mus musculus
Ensembl Gene ENSMUSG00000020230
Encoded Proteins
IDBP-164627
protein arginine N-methyltransferase 2
IDBP-164629
protein arginine N-methyltransferase 2
IDBP-164631
protein arginine N-methyltransferase 2
IDBP-710624
IDBP-713181
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000160310:
Gene Information
Type Protein coding
Genomic Location Chromosome 10:76207222-76237865
Strand Reverse strand
Band C1
Transcripts
ENSMUST00000099572 ENSMUSP00000097167
ENSMUST00000099571 ENSMUSP00000097166
ENSMUST00000020452 ENSMUSP00000020452
ENSMUST00000128099 ENSMUSP00000137707
ENSMUST00000137857 ENSMUSP00000137725
ENSMUST00000144670
ENSMUST00000128048
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 19 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003713 transcription coactivator activity
GO:0005515 protein binding
GO:0008168 methyltransferase activity
GO:0008276 protein methyltransferase activity
GO:0016740 transferase activity
GO:0030331 estrogen receptor binding
GO:0033142 progesterone receptor binding
GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity
GO:0042054 histone methyltransferase activity
GO:0042803 protein homodimerization activity
GO:0042974 retinoic acid receptor binding
GO:0042975 peroxisome proliferator activated receptor binding
GO:0046966 thyroid hormone receptor binding
GO:0050681 androgen receptor binding
Biological Process
GO:0006479 protein methylation
GO:0016571 histone methylation
GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0043065 positive regulation of apoptotic process
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0060765 regulation of androgen receptor signaling pathway
GO:0097194 execution phase of apoptosis
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000160310
View Gene Order
ENSBTAG00000005503
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_2
AndrogenReceptor pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.32020
RefSeq NM_001077638 NM_133182 XM_006513252
OMIM
CCDS CCDS35942
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca