InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Prmt2

Summary

InnateDB Gene

IDBG-164625.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Prmt2

Gene Name

protein arginine N-methyltransferase 2

Synonyms

AI504737; Hrmt1l1;

Species

Mus musculus

Ensembl Gene

ENSMUSG00000020230

Encoded Proteins

IDBP-164627

protein arginine N-methyltransferase 2

IDBP-164629

protein arginine N-methyltransferase 2

IDBP-164631

protein arginine N-methyltransferase 2

IDBP-710624

IDBP-713181

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000160310:

Gene Information

Type

Protein coding

Genomic Location

Chromosome 10:76207222-76237865

Strand

Reverse strand

Band

Transcripts

ENSMUST00000099572	ENSMUSP00000097167
ENSMUST00000099571	ENSMUSP00000097166
ENSMUST00000020452	ENSMUSP00000020452
ENSMUST00000128099	ENSMUSP00000137707
ENSMUST00000137857	ENSMUSP00000137725
ENSMUST00000144670
ENSMUST00000128048

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	19 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003713	transcription coactivator activity
GO:0005515	protein binding
GO:0008168	methyltransferase activity
GO:0008276	protein methyltransferase activity
GO:0016740	transferase activity
GO:0030331	estrogen receptor binding
GO:0033142	progesterone receptor binding
GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity
GO:0042054	histone methyltransferase activity
GO:0042803	protein homodimerization activity
GO:0042974	retinoic acid receptor binding
GO:0042975	peroxisome proliferator activated receptor binding
GO:0046966	thyroid hormone receptor binding
GO:0050681	androgen receptor binding

Biological Process

GO:0006479	protein methylation
GO:0016571	histone methylation
GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine
GO:0032088	negative regulation of NF-kappaB transcription factor activity
GO:0043065	positive regulation of apoptotic process
GO:0045892	negative regulation of transcription, DNA-templated
GO:0045893	positive regulation of transcription, DNA-templated
GO:0060765	regulation of androgen receptor signaling pathway
GO:0097194	execution phase of apoptosis

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005829	cytosol

Orthologs

Species

Homo sapiens

Bos taurus

Gene ID

Gene Order

Method

Confidence

Comments

ENSG00000160310

View Gene Order

Ortholuge

SSD Ortholog

Ortholog supports species divergence

ENSBTAG00000005503

Not yet available

Ortholuge

SSD Ortholog

Ortholog supports species divergence

Pathway Predictions based on Human Orthology Data

NETPATH

NetPath_2

AndrogenReceptor pathway

REACTOME

KEGG

INOH

PID BIOCARTA

PID NCI

Cross-References

SwissProt

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

Mm.32020

RefSeq

NM_001077638 NM_133182 XM_006513252

OMIM

CCDS

CCDS35942

HPRD

IMGT

MGI ID

MGI Symbol

EMBL

GenPept

RNA Seq Atlas