Homo sapiens Gene: CIDEC
Summary
InnateDB Gene IDBG-16636.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CIDEC
Gene Name cell death-inducing DFFA-like effector c
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000187288
Encoded Proteins
cell death-inducing DFFA-like effector c
cell death-inducing DFFA-like effector c
cell death-inducing DFFA-like effector c
cell death-inducing DFFA-like effector c
cell death-inducing DFFA-like effector c
cell death-inducing DFFA-like effector c
cell death-inducing DFFA-like effector c
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the cell death-inducing DNA fragmentation factor-like effector family. Members of this family play important roles in apoptosis. The encoded protein promotes lipid droplet formation in adipocytes and may mediate adipocyte apoptosis. This gene is regulated by insulin and its expression is positively correlated with insulin sensitivity. Mutations in this gene may contribute to insulin resistant diabetes. A pseudogene of this gene is located on the short arm of chromosome 3. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:9866711-9880254
Strand Reverse strand
Band p25.3
Transcripts
ENST00000336832 ENSP00000338642
ENST00000383817 ENSP00000373328
ENST00000423850 ENSP00000400649
ENST00000455015 ENSP00000392975
ENST00000430427 ENSP00000408631
ENST00000443115 ENSP00000411356
ENST00000487454
ENST00000618572 ENSP00000483641
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006915 apoptotic process
GO:0034389 lipid particle organization
GO:0042981 regulation of apoptotic process
GO:0097194 execution phase of apoptosis
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005783 endoplasmic reticulum
GO:0005811 lipid particle
GO:0005829 cytosol
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q96AQ7
TrEMBL
UniProt Splice Variant
Entrez Gene 63924
UniGene Hs.567562
RefSeq XM_005265376 NM_001199551 NM_001199552 NM_001199623 NM_022094 XM_005265374 XM_005265375
HUGO HGNC:24229
OMIM 612120
CCDS CCDS2587 CCDS56239 CCDS74897
HPRD 13060
IMGT
EMBL AC018809 AF303893 AK024524 AK024530 AY364638 AY364640 BC016851 CD518729
GenPept AAH16851 AAN32612 AAQ65242 AAR23106 BAB14920 BAB14922
RNA Seq Atlas 63924