Homo sapiens Gene: TRIP11
Summary
InnateDB Gene IDBG-16648.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TRIP11
Gene Name thyroid hormone receptor interactor 11
Synonyms ACG1A; CEV14; GMAP-210; TRIP-11; TRIP230;
Species Homo sapiens
Ensembl Gene ENSG00000100815
Encoded Proteins
thyroid hormone receptor interactor 11
thyroid hormone receptor interactor 11
thyroid hormone receptor interactor 11
thyroid hormone receptor interactor 11
thyroid hormone receptor interactor 11
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene was identified based on the interaction of its protein product with thyroid hormone receptor beta. This protein is associated with the Golgi apparatus. The N-terminal region of the protein binds Golgi membranes and the C-terminal region binds the minus ends of microtubules; thus, the protein is thought to play a role in assembly and maintenance of the Golgi ribbon structure around the centrosome. Mutations in this gene cause achondrogenesis type IA.[provided by RefSeq, Mar 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:91965991-92040896
Strand Reverse strand
Band q32.12
Transcripts
ENST00000267622 ENSP00000267622
ENST00000554357 ENSP00000451032
ENST00000557017 ENSP00000451607
ENST00000555516 ENSP00000451944
ENST00000555105
ENST00000620738 ENSP00000481111
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 14 [view]
Protein-Protein 13 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003713 transcription coactivator activity
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0000042 protein targeting to Golgi
GO:0003281 ventricular septum development
GO:0006366 transcription from RNA polymerase II promoter
GO:0006412 translation
GO:2001141 regulation of RNA biosynthetic process
Cellular Component
GO:0002079 inner acrosomal membrane
GO:0002080 acrosomal membrane
GO:0002081 outer acrosomal membrane
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005794 Golgi apparatus
GO:0005801 cis-Golgi network
GO:0005840 ribosome
GO:0005856 cytoskeleton
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.591417 Hs.600848 Hs.627136 Hs.632339 Hs.712145 Hs.713299
RefSeq NM_004239 XM_005268213 XM_005268214 XM_006720321
HUGO
OMIM
CCDS CCDS9899
HPRD 05143
IMGT
EMBL
GenPept
RNA Seq Atlas