Version 5.4
Mus musculus Gene: H2-K1
Summary
InnateDB Gene IDBG-168781.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol H2-K1
Gene Name histocompatibility 2, K1, K region
Synonyms H-2K; H-2K(d); H2-K; K-f
Species Mus musculus
Ensembl Gene ENSMUSG00000061232
Encoded Proteins
IDBP-168783
histocompatibility 2, K1, K region
IDBP-168785
histocompatibility 2, K1, K region
IDBP-626826
histocompatibility 2, K1, K region
IDBP-626837
histocompatibility 2, K1, K region
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 17:33996017-34000333
Strand Reverse strand
Band B1
Transcripts
ENSMUST00000025181 ENSMUSP00000025181
ENSMUST00000087189 ENSMUSP00000084436
ENSMUST00000114311
ENSMUST00000172912 ENSMUSP00000134004
ENSMUST00000173602
ENSMUST00000173543
ENSMUST00000173317
ENSMUST00000173075 ENSMUSP00000133847
ENSMUST00000172782
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0005515 protein binding
GO:0042605 peptide antigen binding
Biological Process
GO:0001916 positive regulation of T cell mediated cytotoxicity
GO:0002485 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent
GO:0006955 immune response
GO:0019882 antigen processing and presentation
GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042742 defense response to bacterium
GO:0048839 inner ear development
Cellular Component
GO:0009897 external side of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030670 phagocytic vesicle membrane
GO:0042612 MHC class I protein complex
GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_236645
Class I MHC mediated antigen processing & presentation pathway
REACT_202937
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell pathway
REACT_233584
Cytokine Signaling in Immune system pathway
REACT_230745
Immune System pathway
REACT_199105
ER-Phagosome pathway pathway
REACT_199112
Endosomal/Vacuolar pathway pathway
REACT_198660
Interferon gamma signaling pathway
REACT_198666
Interferon Signaling pathway
REACT_199113
Antigen processing-Cross presentation pathway
REACT_229531
Adaptive Immune System pathway
REACT_246972
Antigen Presentation: Folding, assembly and peptide loading of class I MHC pathway
KEGG
mmu04514
Cell adhesion molecules (CAMs) pathway
mmu04940
Type I diabetes mellitus pathway
mmu04612
Antigen processing and presentation pathway
mmu04650
Natural killer cell mediated cytotoxicity pathway
mmu05330
Allograft rejection pathway
mmu05332
Graft-versus-host disease pathway
mmu05320
Autoimmune thyroid disease pathway
mmu04144
Endocytosis pathway
mmu05416
Viral myocarditis pathway
mmu04145
Phagosome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.382902 Mm.422886
RefSeq NM_001001892 XM_006523674 XM_006523676 XM_006523677 XM_006523678 XM_006523679 XM_006523680 XM_006525307 XM_006525309 XM_006525310 XM_006525311 XM_006525312 XM_006525313
OMIM
CCDS CCDS50069
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca