Version 5.4
Mus musculus Gene: Trmu
Summary
InnateDB Gene IDBG-170915.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Trmu
Gene Name tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
Synonyms 1110005N20Rik; 1600025P05Rik; AI314320; Trmt1
Species Mus musculus
Ensembl Gene ENSMUSG00000022386
Encoded Proteins
IDBP-170917
tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
IDBP-540267
tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
IDBP-532838
tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
IDBP-536966
tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000100416:
This gene is a member of the trmU family. It encodes a mitochondria-specific tRNA-modifying enzyme that is required for the 2-thio modification of 5-taurinomethyl-2-thiouridine tRNA-Lys on the wobble position of the anticodon. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:85879312-85897394
Strand Forward strand
Band E2
Transcripts
ENSMUST00000023019 ENSMUSP00000023019
ENSMUST00000162491 ENSMUSP00000125704
ENSMUST00000160733 ENSMUSP00000125331
ENSMUST00000162601
ENSMUST00000162339 ENSMUSP00000125266
ENSMUST00000161784
ENSMUST00000162010
ENSMUST00000159362
ENSMUST00000159730
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000049 tRNA binding
GO:0003674 molecular_function
GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity
GO:0004810 tRNA adenylyltransferase activity
GO:0005524 ATP binding
GO:0016740 transferase activity
GO:0016783 sulfurtransferase activity
Biological Process
GO:0006529 asparagine biosynthetic process
GO:0008033 tRNA processing
GO:0008150 biological_process
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000100416
View Gene Order
ENSBTAG00000005595
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04122
Sulfur relay system pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04122
Sulfur relay system pathway
INOH
PID NCI
Cross-References
SwissProt Q9DAT5
TrEMBL E0CZ49
UniProt Splice Variant
Entrez Gene 72026
UniGene
RefSeq NM_028063
OMIM
CCDS CCDS27726
HPRD
IMGT
MGI ID MGI:1919276
MGI Symbol Trmu
EMBL AC139513 AK005541 AK043532 AK044059 AY349617 BC061026
GenPept AAH61026 AAQ55218 BAB24110 BAC31570 BAC31758
RNA Seq Atlas 72026

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca