Mus musculus Gene: Adamts9
Summary
InnateDB Gene IDBG-171267.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Adamts9
Gene Name a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 9
Synonyms 1810011L16Rik; 8430403M15Rik; AW743315; E030027K14Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000030022
Encoded Proteins
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 9
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 9
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000163638:
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. Members of the ADAMTS family have been implicated in the cleavage of proteoglycans, the control of organ shape during development, and the inhibition of angiogenesis. This gene is localized to chromosome 3p14.3-p14.2, an area known to be lost in hereditary renal tumors. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:92772699-92943492
Strand Reverse strand
Band D1
Transcripts
ENSMUST00000113438 ENSMUSP00000109065
ENSMUST00000125490
ENSMUST00000130314
ENSMUST00000136751
ENSMUST00000167391 ENSMUSP00000126498
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004175 endopeptidase activity
GO:0004222 metalloendopeptidase activity
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
GO:0045636 positive regulation of melanocyte differentiation
GO:0048070 regulation of developmental pigmentation
Cellular Component
GO:0005578 proteinaceous extracellular matrix
GO:0005615 extracellular space
GO:0031012 extracellular matrix
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Post-translational protein modification pathway
Extracellular matrix organization pathway
Degradation of the extracellular matrix pathway
O-linked glycosylation pathway
Metabolism of proteins pathway
O-glycosylation of TSR domain-containing proteins pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E9PUN6 E9PYV8
UniProt Splice Variant
Entrez Gene 101401
UniGene Mm.158235 Mm.257557 Mm.400047
RefSeq NM_175314 XM_006505260
OMIM
CCDS CCDS51855
HPRD
IMGT
MGI ID MGI:1916320
MGI Symbol Adamts9
EMBL AC110378 AC166101
GenPept
RNA Seq Atlas 101401