Version 5.4
Mus musculus Gene: Neo1
Summary
InnateDB Gene IDBG-172288.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Neo1
Gene Name neogenin
Synonyms 2610028H22Rik; AI327052; D930014N22Rik; Igdcc2
Species Mus musculus
Ensembl Gene ENSMUSG00000032340
Encoded Proteins
IDBP-172290
neogenin
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000067141:
This gene encodes a cell surface protein that is a member of the immunoglobulin superfamily. The encoded protein consists of four N-terminal immunoglobulin-like domains, six fibronectin type III domains, a transmembrane domain and a C-terminal internal domain that shares homology with the tumor suppressor candidate gene DCC. This protein may be involved in cell growth and differentiation and in cell-cell adhesion. Defects in this gene are associated with cell proliferation in certain cancers. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:58874679-59036441
Strand Reverse strand
Band B
Transcripts
ENSMUST00000068664 ENSMUSP00000063656
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0005515 protein binding
GO:0045296 cadherin binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0007520 myoblast fusion
GO:0055072 iron ion homeostasis
Cellular Component
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000067141
View Gene Order
ENSBTAG00000004990
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04514
Cell adhesion molecules (CAMs) pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_21402
CDO in myogenesis pathway
REACT_22237
Netrin-1 signaling pathway
REACT_111045
Developmental Biology pathway
REACT_18266
Axon guidance pathway
REACT_21303
Myogenesis pathway
KEGG
hsa04514
Cell adhesion molecules (CAMs) pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E9QK04 Q7TQG5
UniProt Splice Variant
Entrez Gene 18007
UniGene Mm.403752 Mm.408057 Mm.42249
RefSeq NM_001042752 NM_008684
OMIM
CCDS CCDS23246
HPRD
IMGT
MGI ID MGI:1097159
MGI Symbol Neo1
EMBL AC110530 BC054540 CT033754
GenPept AAH54540
RNA Seq Atlas 18007

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca