Mus musculus Gene: Junb
Summary
InnateDB Gene IDBG-175664.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Junb
Gene Name Jun-B oncogene
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000052837
Encoded Proteins
Jun-B oncogene
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000171223:
Gene Information
Type Protein coding
Genomic Location Chromosome 8:84976909-84978748
Strand Reverse strand
Band C3
Transcripts
ENSMUST00000064922 ENSMUSP00000064680
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 28 experimentally validated interaction(s) in this database.
They are also associated with 44 interaction(s) predicted by orthology.
Experimentally validated
Total 28 [view]
Protein-Protein 12 [view]
Protein-DNA 16 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 44 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding
GO:0003677 DNA binding
GO:0003690 double-stranded DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0001570 vasculogenesis
GO:0001649 osteoblast differentiation
GO:0001701 in utero embryonic development
GO:0001829 trophectodermal cell differentiation
GO:0006355 regulation of transcription, DNA-templated
GO:0006366 transcription from RNA polymerase II promoter
GO:0007565 female pregnancy
GO:0009416 response to light stimulus
GO:0009612 response to mechanical stimulus
GO:0009987 cellular process
GO:0014070 response to organic cyclic compound
GO:0030316 osteoclast differentiation
GO:0032570 response to progesterone
GO:0032870 cellular response to hormone stimulus
GO:0033687 osteoblast proliferation
GO:0034097 response to cytokine
GO:0042493 response to drug
GO:0043434 response to peptide hormone
GO:0045597 positive regulation of cell differentiation
GO:0046697 decidualization
GO:0051412 response to corticosterone
GO:0051591 response to cAMP
GO:0051726 regulation of cell cycle
GO:0060136 embryonic process involved in female pregnancy
GO:0060716 labyrinthine layer blood vessel development
GO:0071277 cellular response to calcium ion
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
Osteoclast differentiation pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
TGF_beta_Receptor pathway
TNFalpha pathway
BCR pathway
TSLP pathway
Oncostatin_M pathway
REACTOME
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription pathway
Generic Transcription Pathway pathway
SMAD4 MH2 Domain Mutants in Cancer pathway
Loss of Function of SMAD4 in Cancer pathway
Loss of Function of SMAD2/3 in Cancer pathway
Signaling by TGF-beta Receptor Complex in Cancer pathway
TGFBR2 MSI Frameshift Mutants in Cancer pathway
Signal Transduction pathway
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer pathway
SMAD2/3 MH2 Domain Mutants in Cancer pathway
Loss of Function of TGFBR2 in Cancer pathway
SMAD2/3 Phosphorylation Motif Mutants in Cancer pathway
TGFBR1 KD Mutants in Cancer pathway
Loss of Function of TGFBR1 in Cancer pathway
TGFBR1 LBD Mutants in Cancer pathway
TGFBR2 Kinase Domain Mutants in Cancer pathway
Gene Expression pathway
Disease pathway
Signaling by TGF-beta Receptor Complex pathway
KEGG
Osteoclast differentiation pathway
INOH
PID NCI
Calcium signaling in the CD4+ TCR pathway
Validated transcriptional targets of AP1 family members Fra1 and Fra2
Downstream signaling in na´ve CD8+ T cells
Calcineurin-regulated NFAT-dependent transcription in lymphocytes
ATF-2 transcription factor network
AP-1 transcription factor network
IL6-mediated signaling events
Cross-References
SwissProt P09450
TrEMBL Q3U0S8 Q569U6
UniProt Splice Variant
Entrez Gene 16477
UniGene Mm.1167 Mm.486918
RefSeq NM_008416
OMIM
CCDS CCDS22488
HPRD
IMGT
MGI ID MGI:96647
MGI Symbol Junb
EMBL AK088643 AK141592 AK145550 AK150111 AK150247 AK150286 AK156596 AK159083 AK159520 AK160066 BC003790 BC092302 CH466525 J03236 U20735 X54332
GenPept AAA39343 AAA74916 AAH03790 AAH92302 BAC40473 BAE24752 BAE26502 BAE29315 BAE29411 BAE29441 BAE33773 BAE34801 BAE35149 BAE35602 EDL10979
RNA Seq Atlas 16477