Version 5.4
Mus musculus Gene: Sec13
Summary
InnateDB Gene IDBG-178462.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sec13
Gene Name SEC13 homolog (S. cerevisiae)
Synonyms 1110003H02Rik; Sec13l1; Sec13r
Species Mus musculus
Ensembl Gene ENSMUSG00000030298
Encoded Proteins
IDBP-178464
SEC13 homolog (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000157020:
The protein encoded by this gene belongs to the SEC13 family of WD-repeat proteins. It is a constituent of the endoplasmic reticulum and the nuclear pore complex. It has similarity to the yeast SEC13 protein, which is required for vesicle biogenesis from endoplasmic reticulum during the transport of proteins. Multiple alternatively spliced transcript variants have been found. [provided by RefSeq, Oct 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:113728067-113740743
Strand Reverse strand
Band E3
Transcripts
ENSMUST00000032440 ENSMUSP00000032440
ENSMUST00000138204
ENSMUST00000145979
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 22 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006888 ER to Golgi vesicle-mediated transport
GO:0015031 protein transport
GO:0051028 mRNA transport
Cellular Component
GO:0000776 kinetochore
GO:0005635 nuclear envelope
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0012507 ER to Golgi transport vesicle membrane
GO:0031080 nuclear pore outer ring
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000157020
View Gene Order
ENSBTAG00000017825
Not yet available
Pathways
NETPATH
REACTOME
REACT_249770
Cell Cycle, Mitotic pathway
REACT_205304
COPII (Coat Protein 2) Mediated Vesicle Transport pathway
REACT_236645
Class I MHC mediated antigen processing & presentation pathway
REACT_206143
Transport to the Golgi and subsequent modification pathway
REACT_207679
Separation of Sister Chromatids pathway
REACT_198961
Resolution of Sister Chromatid Cohesion pathway
REACT_209837
Membrane Trafficking pathway
REACT_188804
Cell Cycle pathway
REACT_230745
Immune System pathway
REACT_241408
M Phase pathway
REACT_247926
Metabolism of proteins pathway
REACT_236283
Post-translational protein modification pathway
REACT_196550
MHC class II antigen presentation pathway
REACT_199403
Mitotic Metaphase and Anaphase pathway
REACT_256756
Mitotic Prometaphase pathway
REACT_203486
ER to Golgi Transport pathway
REACT_237472
Asparagine N-linked glycosylation pathway
REACT_229531
Adaptive Immune System pathway
REACT_202512
Mitotic Anaphase pathway
REACT_246972
Antigen Presentation: Folding, assembly and peptide loading of class I MHC pathway
KEGG
mmu03013
RNA transport pathway
mmu04141
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_150425
Resolution of Sister Chromatid Cohesion pathway
REACT_682
Mitotic Prometaphase pathway
REACT_150471
Separation of Sister Chromatids pathway
REACT_75795
Antigen Presentation: Folding, assembly and peptide loading of class I MHC pathway
REACT_121399
MHC class II antigen presentation pathway
REACT_12507
COPII (Coat Protein 2) Mediated Vesicle Transport pathway
REACT_25046
Transport to the Golgi and subsequent modification pathway
REACT_22426
Asparagine N-linked glycosylation pathway
REACT_22161
Post-translational protein modification pathway
REACT_11203
ER to Golgi Transport pathway
REACT_115566
Cell Cycle pathway
REACT_17015
Metabolism of proteins pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
REACT_910
M Phase pathway
REACT_1275
Mitotic Anaphase pathway
REACT_152
Cell Cycle, Mitotic pathway
REACT_75820
Class I MHC mediated antigen processing & presentation pathway
REACT_11123
Membrane Trafficking pathway
REACT_150314
Mitotic Metaphase and Anaphase pathway
REACT_216366
M Phase pathway
REACT_218212
Antigen Presentation: Folding, assembly and peptide loading of class I MHC pathway
REACT_214728
Transport to the Golgi and subsequent modification pathway
REACT_212887
Separation of Sister Chromatids pathway
REACT_212672
Class I MHC mediated antigen processing & presentation pathway
REACT_215084
Mitotic Metaphase and Anaphase pathway
REACT_211185
Mitotic Anaphase pathway
REACT_213138
Immune System pathway
REACT_215505
Cell Cycle, Mitotic pathway
REACT_223866
Asparagine N-linked glycosylation pathway
REACT_214934
Cell Cycle pathway
REACT_211133
MHC class II antigen presentation pathway
REACT_213782
Metabolism of proteins pathway
REACT_214405
Post-translational protein modification pathway
REACT_225088
ER to Golgi Transport pathway
REACT_220924
COPII (Coat Protein 2) Mediated Vesicle Transport pathway
REACT_209545
Resolution of Sister Chromatid Cohesion pathway
REACT_214469
Adaptive Immune System pathway
REACT_203101
Mitotic Prometaphase pathway
REACT_213260
Membrane Trafficking pathway
KEGG
hsa03013
RNA transport pathway
hsa04141
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Cross-References
SwissProt Q9D1M0
TrEMBL
UniProt Splice Variant
Entrez Gene 110379
UniGene Mm.465981
RefSeq NM_024206
OMIM
CCDS CCDS39596
HPRD
IMGT
MGI ID MGI:99832
MGI Symbol Sec13
EMBL AK003354 AK009755 BC002128
GenPept AAH02128 BAB22732 BAB26480
RNA Seq Atlas 110379

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca