Mus musculus Gene: Shroom2
Summary
InnateDB Gene IDBG-180473.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Shroom2
Gene Name shroom family member 2
Synonyms 4832440C16; Apxl; C630003H05Rik; Shrm2;
Species Mus musculus
Ensembl Gene ENSMUSG00000045180
Encoded Proteins
shroom family member 2
shroom family member 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000146950:
The protein encoded by this gene shares significant similarities with the apical protein from Xenopus laevis which is implicated in amiloride-sensitive sodium channel activity. This gene is a strong candidate gene for ocular albinism type 1 syndrome. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome X:152609509-152769465
Strand Reverse strand
Band F3
Transcripts
ENSMUST00000062317 ENSMUSP00000057500
ENSMUST00000101141 ENSMUSP00000098701
ENSMUST00000137217
ENSMUST00000152746
ENSMUST00000124141
ENSMUST00000141677
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0019904 protein domain specific binding
GO:0051015 actin filament binding
Biological Process
GO:0000902 cell morphogenesis
GO:0002089 lens morphogenesis in camera-type eye
GO:0007420 brain development
GO:0008057 eye pigment granule organization
GO:0016477 cell migration
GO:0030835 negative regulation of actin filament depolymerization
GO:0032401 establishment of melanosome localization
GO:0032438 melanosome organization
GO:0043010 camera-type eye development
GO:0043482 cellular pigment accumulation
GO:0043583 ear development
GO:0045176 apical protein localization
GO:0045217 cell-cell junction maintenance
GO:0048593 camera-type eye morphogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005874 microtubule
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0005913 cell-cell adherens junction
GO:0005923 tight junction
GO:0005938 cell cortex
GO:0016324 apical plasma membrane
GO:0030864 cortical actin cytoskeleton
GO:0031941 filamentous actin
GO:0043025 neuronal cell body
GO:0043296 apical junction complex
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
Method
Confidence
Comments
Low
Tentative data, uncurated. RBBH derived.
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.401618 Mm.40796 Mm.412816
RefSeq NM_001290684 NM_001290686 NM_001290687 NM_172441 XM_006528683 XM_006528684
OMIM
CCDS CCDS41179 CCDS72455
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas