Version 5.4
Mus musculus Gene: Shroom2
Summary
InnateDB Gene IDBG-180473.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Shroom2
Gene Name shroom family member 2
Synonyms 4832440C16; Apxl; C630003H05Rik; Shrm2
Species Mus musculus
Ensembl Gene ENSMUSG00000045180
Encoded Proteins
IDBP-180475
shroom family member 2
IDBP-180477
shroom family member 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000146950:
The protein encoded by this gene shares significant similarities with the apical protein from Xenopus laevis which is implicated in amiloride-sensitive sodium channel activity. This gene is a strong candidate gene for ocular albinism type 1 syndrome. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome X:152609509-152769465
Strand Reverse strand
Band F3
Transcripts
ENSMUST00000062317 ENSMUSP00000057500
ENSMUST00000101141 ENSMUSP00000098701
ENSMUST00000137217
ENSMUST00000152746
ENSMUST00000124141
ENSMUST00000141677
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
GO:0005515 protein binding
GO:0008013 beta-catenin binding
GO:0019904 protein domain specific binding
GO:0051015 actin filament binding
Biological Process
GO:0000902 cell morphogenesis
GO:0002089 lens morphogenesis in camera-type eye
GO:0007420 brain development
GO:0008057 eye pigment granule organization
GO:0016477 cell migration
GO:0030835 negative regulation of actin filament depolymerization
GO:0032401 establishment of melanosome localization
GO:0032438 melanosome organization
GO:0043010 camera-type eye development
GO:0043482 cellular pigment accumulation
GO:0043583 ear development
GO:0045176 apical protein localization
GO:0045217 cell-cell junction maintenance
GO:0048593 camera-type eye morphogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005874 microtubule
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0005913 cell-cell adherens junction
GO:0005923 tight junction
GO:0005938 cell cortex
GO:0016324 apical plasma membrane
GO:0030864 cortical actin cytoskeleton
GO:0031941 filamentous actin
GO:0043025 neuronal cell body
GO:0043296 apical junction complex
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000146950
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.401618 Mm.40796 Mm.412816
RefSeq NM_001290684 NM_001290686 NM_001290687 NM_172441 XM_006528683 XM_006528684
OMIM
CCDS CCDS41179 CCDS72455
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca