Version 5.4
| Mus musculus Gene: Adcy6 | |||||||||||||||
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| Summary | |||||||||||||||
| InnateDB Gene | IDBG-180609.6 | ||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||
| Gene Symbol | Adcy6 | ||||||||||||||
| Gene Name | adenylate cyclase 6 | ||||||||||||||
| Synonyms | AC6; mKIAA0422; | ||||||||||||||
| Species | Mus musculus | ||||||||||||||
| Ensembl Gene | ENSMUSG00000022994 | ||||||||||||||
| Encoded Proteins |
adenylate cyclase 6
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| Protein Structure | |||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||
| Entrez Gene | |||||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000174233:
This gene encodes adenylate cyclase 6, which is a membrane-associated enzyme and catalyzes the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). The expression of this gene is found in normal thyroid and brain tissues, as well as some tumors; and its expression is significantly higher in one hyperfunctioning thyroid tumor than in normal thyroid tissue. Alternative splicing generates 2 transcript variants. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||||||
| Type | Protein coding | ||||||||||||||
| Genomic Location | Chromosome 15:98589994-98607633 | ||||||||||||||
| Strand | Reverse strand | ||||||||||||||
| Band | F1 | ||||||||||||||
| Transcripts |
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| Interactions | |||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Method
Confidence
Comments
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| Pathways | |||||||||||||||
| NETPATH | |||||||||||||||
| REACTOME | |||||||||||||||
| KEGG |
Purine metabolism pathway
Chemokine signaling pathway pathway
Oocyte meiosis pathway
Vascular smooth muscle contraction pathway
Gap junction pathway
Taste transduction pathway
GnRH signaling pathway pathway
Progesterone-mediated oocyte maturation pathway
Melanogenesis pathway
Vasopressin-regulated water reabsorption pathway
Salivary secretion pathway
Gastric acid secretion pathway
Pancreatic secretion pathway
Bile secretion pathway
Dilated cardiomyopathy pathway
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| INOH | |||||||||||||||
| PID BIOCARTA | |||||||||||||||
| PID NCI | |||||||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||||||
| NETPATH | |||||||||||||||
| REACTOME |
G alpha (s) signalling events pathway
Signaling by FGFR in disease pathway
Integration of energy metabolism pathway
Transmembrane transport of small molecules pathway
Adenylate cyclase activating pathway pathway
CaM pathway pathway
Signalling by NGF pathway
Vasopressin regulates renal water homeostasis via Aquaporins pathway
PKA-mediated phosphorylation of CREB pathway
Signaling by Hedgehog pathway
Signaling by EGFR in Cancer pathway
Downstream signaling of activated FGFR pathway
Phospholipase C-mediated cascade pathway
Adenylate cyclase inhibitory pathway pathway
DAP12 signaling pathway
Adrenaline,noradrenaline inhibits insulin secretion pathway
Neuronal System pathway
Signaling by EGFR pathway
Signaling by GPCR pathway
Innate Immune System pathway
PLC beta mediated events pathway
GABA receptor activation pathway
Glucagon signaling in metabolic regulation pathway
PLC-gamma1 signalling pathway
Opioid Signalling pathway
Activation of GABAB receptors pathway
DAG and IP3 signaling pathway
PKA activation pathway
Signal Transduction pathway
GPCR downstream signaling pathway
G alpha (i) signalling events pathway
Hedgehog 'off' state pathway
G-protein mediated events pathway
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion pathway
Immune System pathway
Downstream signal transduction pathway
G alpha (z) signalling events pathway
GABA B receptor activation pathway
NGF signalling via TRKA from the plasma membrane pathway
Transmission across Chemical Synapses pathway
Signaling by FGFR pathway
Regulation of insulin secretion pathway
Signaling by PDGF pathway
PKA activation in glucagon signalling pathway
Signaling by ERBB2 pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
Metabolism pathway
Inhibition of adenylate cyclase pathway pathway
PLCG1 events in ERBB2 signaling pathway
Ca-dependent events pathway
Calmodulin induced events pathway
Aquaporin-mediated transport pathway
Disease pathway
DAP12 interactions pathway
EGFR interacts with phospholipase C-gamma pathway
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| KEGG |
Purine metabolism pathway
Chemokine signaling pathway pathway
Oocyte meiosis pathway
Vascular smooth muscle contraction pathway
Gap junction pathway
Taste transduction pathway
GnRH signaling pathway pathway
Progesterone-mediated oocyte maturation pathway
Melanogenesis pathway
Vasopressin-regulated water reabsorption pathway
Salivary secretion pathway
Gastric acid secretion pathway
Pancreatic secretion pathway
Bile secretion pathway
Dilated cardiomyopathy pathway
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| INOH |
GPCR signaling pathway
GPCR Adenosine A2A receptor signaling pathway pathway
Purine nucleotides nucleosides metabolism pathway
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| PID BIOCARTA | |||||||||||||||
| PID NCI | |||||||||||||||
| Cross-References | |||||||||||||||
| SwissProt | |||||||||||||||
| TrEMBL | F8VQ52 | ||||||||||||||
| UniProt Splice Variant | |||||||||||||||
| Entrez Gene | 11512 | ||||||||||||||
| UniGene | Mm.157091 | ||||||||||||||
| RefSeq | NM_007405 XM_006520304 XM_006520305 XM_006520306 XM_006520307 XM_006520308 XM_006520309 XM_006520310 XM_006520311 XM_006520312 XM_006520313 XM_006520314 XM_006520315 XM_006520316 | ||||||||||||||
| OMIM | |||||||||||||||
| CCDS | CCDS27799 | ||||||||||||||
| HPRD | |||||||||||||||
| IMGT | |||||||||||||||
| MGI ID | MGI:87917 | ||||||||||||||
| MGI Symbol | Adcy6 | ||||||||||||||
| EMBL | AC138221 | ||||||||||||||
| GenPept | |||||||||||||||
| RNA Seq Atlas | 11512 | ||||||||||||||