Mus musculus Gene: Adcy6
Summary
InnateDB Gene IDBG-180609.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Adcy6
Gene Name adenylate cyclase 6
Synonyms AC6; mKIAA0422;
Species Mus musculus
Ensembl Gene ENSMUSG00000022994
Encoded Proteins
adenylate cyclase 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000174233:
This gene encodes adenylate cyclase 6, which is a membrane-associated enzyme and catalyzes the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). The expression of this gene is found in normal thyroid and brain tissues, as well as some tumors; and its expression is significantly higher in one hyperfunctioning thyroid tumor than in normal thyroid tissue. Alternative splicing generates 2 transcript variants. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:98589994-98607633
Strand Reverse strand
Band F1
Transcripts
ENSMUST00000096224 ENSMUSP00000093939
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0004016 adenylate cyclase activity
GO:0005515 protein binding
GO:0016849 phosphorus-oxygen lyase activity
Biological Process
GO:0006171 cAMP biosynthetic process
GO:0007190 activation of adenylate cyclase activity
GO:0007212 dopamine receptor signaling pathway
GO:0009190 cyclic nucleotide biosynthetic process
GO:0035556 intracellular signal transduction
GO:0071380 cellular response to prostaglandin E stimulus
GO:0071870 cellular response to catecholamine stimulus
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
KEGG
Purine metabolism pathway
Chemokine signaling pathway pathway
Oocyte meiosis pathway
Vascular smooth muscle contraction pathway
Gap junction pathway
Taste transduction pathway
GnRH signaling pathway pathway
Progesterone-mediated oocyte maturation pathway
Melanogenesis pathway
Vasopressin-regulated water reabsorption pathway
Salivary secretion pathway
Gastric acid secretion pathway
Pancreatic secretion pathway
Bile secretion pathway
Dilated cardiomyopathy pathway
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
G alpha (s) signalling events pathway
Signaling by FGFR in disease pathway
Integration of energy metabolism pathway
Transmembrane transport of small molecules pathway
Adenylate cyclase activating pathway pathway
CaM pathway pathway
Signalling by NGF pathway
Vasopressin regulates renal water homeostasis via Aquaporins pathway
PKA-mediated phosphorylation of CREB pathway
Signaling by Hedgehog pathway
Signaling by EGFR in Cancer pathway
Downstream signaling of activated FGFR pathway
Phospholipase C-mediated cascade pathway
Adenylate cyclase inhibitory pathway pathway
DAP12 signaling pathway
Adrenaline,noradrenaline inhibits insulin secretion pathway
Neuronal System pathway
Signaling by EGFR pathway
Signaling by GPCR pathway
Innate Immune System pathway
PLC beta mediated events pathway
GABA receptor activation pathway
Glucagon signaling in metabolic regulation pathway
PLC-gamma1 signalling pathway
Opioid Signalling pathway
Activation of GABAB receptors pathway
DAG and IP3 signaling pathway
PKA activation pathway
Signal Transduction pathway
GPCR downstream signaling pathway
G alpha (i) signalling events pathway
Hedgehog 'off' state pathway
G-protein mediated events pathway
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion pathway
Immune System pathway
Downstream signal transduction pathway
G alpha (z) signalling events pathway
GABA B receptor activation pathway
NGF signalling via TRKA from the plasma membrane pathway
Transmission across Chemical Synapses pathway
Signaling by FGFR pathway
Regulation of insulin secretion pathway
Signaling by PDGF pathway
PKA activation in glucagon signalling pathway
Signaling by ERBB2 pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
Metabolism pathway
Inhibition of adenylate cyclase pathway pathway
PLCG1 events in ERBB2 signaling pathway
Ca-dependent events pathway
Calmodulin induced events pathway
Aquaporin-mediated transport pathway
Disease pathway
DAP12 interactions pathway
EGFR interacts with phospholipase C-gamma pathway
KEGG
Purine metabolism pathway
Chemokine signaling pathway pathway
Oocyte meiosis pathway
Vascular smooth muscle contraction pathway
Gap junction pathway
Taste transduction pathway
GnRH signaling pathway pathway
Progesterone-mediated oocyte maturation pathway
Melanogenesis pathway
Vasopressin-regulated water reabsorption pathway
Salivary secretion pathway
Gastric acid secretion pathway
Pancreatic secretion pathway
Bile secretion pathway
Dilated cardiomyopathy pathway
INOH
GPCR signaling pathway
GPCR Adenosine A2A receptor signaling pathway pathway
Purine nucleotides nucleosides metabolism pathway
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL F8VQ52
UniProt Splice Variant
Entrez Gene 11512
UniGene Mm.157091
RefSeq NM_007405 XM_006520304 XM_006520305 XM_006520306 XM_006520307 XM_006520308 XM_006520309 XM_006520310 XM_006520311 XM_006520312 XM_006520313 XM_006520314 XM_006520315 XM_006520316
OMIM
CCDS CCDS27799
HPRD
IMGT
MGI ID MGI:87917
MGI Symbol Adcy6
EMBL AC138221
GenPept
RNA Seq Atlas 11512