InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Hnrpdl

Summary

InnateDB Gene

IDBG-182715.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Hnrpdl

Gene Name

heterogeneous nuclear ribonucleoprotein D-like

Synonyms

AA407431; AA959857; D5Ertd650e; D5Wsu145e; hnRNP DL; hnRNP-DL; Hnrnpdl1; Hnrpdl; JKTBP

Species

Mus musculus

Ensembl Gene

ENSMUSG00000029328

Encoded Proteins

IDBP-182719

heterogeneous nuclear ribonucleoprotein D-like

IDBP-542786

heterogeneous nuclear ribonucleoprotein D-like

IDBP-538758

heterogeneous nuclear ribonucleoprotein D-like

IDBP-540855

heterogeneous nuclear ribonucleoprotein D-like

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000152795:
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two RRM domains that bind to RNAs. Three alternatively spliced transcript variants have been described for this gene. One of the variants is probably not translated because the transcript is a candidate for nonsense-mediated mRNA decay. The protein isoforms encoded by this gene are similar to its family member HNRPD. [provided by RefSeq, May 2011]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 5:100033577-100039664

Strand

Reverse strand

Band

Transcripts

ENSMUST00000086900	ENSMUSP00000084114
ENSMUST00000128187	ENSMUSP00000121005
ENSMUST00000135424
ENSMUST00000153442	ENSMUSP00000118555
ENSMUST00000141337
ENSMUST00000149384	ENSMUSP00000117589
ENSMUST00000151323

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 60 interaction(s) predicted by orthology.

Experimentally validated
Total	7 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	60 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0003690	double-stranded DNA binding
GO:0003697	single-stranded DNA binding
GO:0003723	RNA binding
GO:0008143	poly(A) binding
GO:0034046	poly(G) binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0010468	regulation of gene expression
GO:0016071	mRNA metabolic process

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0070062	extracellular vesicular exosome

Orthologs

Species

Homo sapiens

Bos taurus

Gene ID

Gene Order

ENSG00000152795

View Gene Order

ENSBTAG00000014804

Not yet available

Pathway Predictions based on Human Orthology Data

NETPATH

NetPath_4

EGFR1 pathway

REACTOME

KEGG

INOH

PID NCI

Cross-References

SwissProt

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

Mm.364217 Mm.389579 Mm.398605 Mm.466977 Mm.467671

RefSeq

NM_016690

OMIM

CCDS

CCDS19460

HPRD

IMGT

MGI ID

MGI Symbol

EMBL

GenPept

RNA Seq Atlas