Mus musculus Gene: Gys1
Summary
InnateDB Gene IDBG-183094.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gys1
Gene Name glycogen synthase 1, muscle
Synonyms Gys3; MGS
Species Mus musculus
Ensembl Gene ENSMUSG00000003865
Encoded Proteins
glycogen synthase 1, muscle
glycogen synthase 1, muscle
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000104812:
The protein encoded by this gene catalyzes the addition of glucose monomers to the growing glycogen molecule through the formation of alpha-1,4-glycoside linkages. Mutations in this gene are associated with muscle glycogen storage disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:45434844-45456619
Strand Forward strand
Band B3
Transcripts
ENSMUST00000003964 ENSMUSP00000003964
ENSMUST00000107766 ENSMUSP00000103395
ENSMUST00000124343
ENSMUST00000130561
ENSMUST00000150689
ENSMUST00000140994
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 4 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 17 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004373 glycogen (starch) synthase activity
GO:0005515 protein binding
GO:0005536 glucose binding
GO:0019901 protein kinase binding
GO:0061547 glycogen synthase activity, transferring glucose-1-phosphate
Biological Process
GO:0005977 glycogen metabolic process
GO:0005978 glycogen biosynthetic process
GO:0007507 heart development
GO:0009058 biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0016234 inclusion body
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Disease pathway
Glucose metabolism pathway
Metabolism pathway
Glycogen synthesis pathway
Glycogen storage diseases pathway
Myoclonic epilepsy of Lafora pathway
Metabolism of carbohydrates pathway
KEGG
Insulin signaling pathway pathway
Starch and sucrose metabolism pathway
INOH
Insulin receptor signaling pathway
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
KitReceptor pathway
REACTOME
Myoclonic epilepsy of Lafora pathway
Glycogen synthesis pathway
Metabolism of carbohydrates pathway
Metabolism pathway
Disease pathway
Glucose metabolism pathway
Glycogen storage diseases pathway
Glycogen synthesis pathway
Metabolism of carbohydrates pathway
Myoclonic epilepsy of Lafora pathway
Glycogen storage diseases pathway
Glucose metabolism pathway
Metabolism pathway
Disease pathway
KEGG
Insulin signaling pathway pathway
Starch and sucrose metabolism pathway
INOH
Insulin receptor signaling pathway
PID NCI
Insulin-mediated glucose transport
Cross-References
SwissProt Q9Z1E4
TrEMBL D3Z0Q6
UniProt Splice Variant
Entrez Gene 14936
UniGene Mm.275654 Mm.480753
RefSeq NM_030678
OMIM
CCDS CCDS21244
HPRD
IMGT
MGI ID MGI:101805
MGI Symbol Gys1
EMBL AC151602 AK050813 AK171148 BC019389 BC131687 BC131688 BC152550 CH466603 U53218 X94616
GenPept AAD09457 AAH19389 AAI31688 AAI31689 AAI52551 BAC34420 BAE42275 CAA64322 EDL22855
RNA Seq Atlas 14936