Version 5.4
Mus musculus Gene: Mov10
Summary
InnateDB Gene IDBG-183109.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mov10
Gene Name Moloney leukemia virus 10
Synonyms C77703; Mov-10
Species Mus musculus
Ensembl Gene ENSMUSG00000002227
Encoded Proteins
IDBP-183111
Moloney leukemia virus 10
IDBP-268054
Moloney leukemia virus 10
IDBP-268056
Moloney leukemia virus 10
IDBP-538440
Moloney leukemia virus 10
IDBP-627059
Moloney leukemia virus 10
IDBP-627061
Moloney leukemia virus 10
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
PMID 23093941
[Homo sapiens] MOV10 associates with LINE1 ribonucleoprotein particles and restricts endogenous retrovirus transposition.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000155363:
Gene Information
Type Protein coding
Genomic Location Chromosome 3:104794836-104818563
Strand Reverse strand
Band F2.2
Transcripts
ENSMUST00000002297 ENSMUSP00000002297
ENSMUST00000106775 ENSMUSP00000102387
ENSMUST00000106774 ENSMUSP00000102386
ENSMUST00000136148 ENSMUSP00000120486
ENSMUST00000145414
ENSMUST00000166979 ENSMUSP00000126897
ENSMUST00000168015 ENSMUSP00000128246
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 47 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 6 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 47 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0004386 helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0017111 nucleoside-triphosphatase activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0008152 metabolic process
GO:0035279 mRNA cleavage involved in gene silencing by miRNA
Cellular Component
GO:0000932 cytoplasmic mRNA processing body
GO:0005615 extracellular space
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000155363
View Gene Order
ENSBTAG00000014297
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_75829
PIP3 activates AKT signaling pathway
REACT_147814
DAP12 signaling pathway
REACT_147694
DAP12 interactions pathway
REACT_12464
PI3K/AKT activation pathway
REACT_12578
GAB1 signalosome pathway
REACT_9417
Signaling by EGFR pathway
REACT_115961
PI3K events in ERBB4 signaling pathway
REACT_115596
Signaling by ERBB4 pathway
REACT_116008
PI3K events in ERBB2 signaling pathway
REACT_115755
Signaling by ERBB2 pathway
REACT_118568
Pre-NOTCH Transcription and Translation pathway
REACT_21270
PI-3K cascade pathway
REACT_9470
Signaling by FGFR pathway
REACT_111040
Signaling by SCF-KIT pathway
REACT_17025
Downstream signal transduction pathway
REACT_16888
Signaling by PDGF pathway
REACT_120736
Signaling by FGFR in disease pathway
REACT_120956
Cellular responses to stress pathway
REACT_169325
Oncogene Induced Senescence pathway
REACT_11061
Signalling by NGF pathway
REACT_115871
Signaling by EGFR in Cancer pathway
REACT_21272
Downstream signaling of activated FGFR pathway
REACT_172761
Ca2+ pathway pathway
REACT_118744
Pre-NOTCH Expression and Processing pathway
REACT_172694
beta-catenin independent WNT signaling pathway
REACT_11045
Signaling by Wnt pathway
REACT_163769
Role of LAT2/NTAL/LAB on calcium mobilization pathway
REACT_6802
Innate Immune System pathway
REACT_163936
Fc epsilon receptor (FCERI) signaling pathway
REACT_111102
Signal Transduction pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
REACT_169274
Cellular Senescence pathway
REACT_12056
NGF signalling via TRKA from the plasma membrane pathway
REACT_299
Signaling by NOTCH pathway
REACT_147723
PI3K/AKT Signaling in Cancer pathway
REACT_118773
Signaling by the B Cell Receptor (BCR) pathway
REACT_169436
Oxidative Stress Induced Senescence pathway
REACT_118638
Downstream signaling events of B Cell Receptor (BCR) pathway
REACT_116125
Disease pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL D3YYR1
UniProt Splice Variant
Entrez Gene 17454
UniGene Mm.1597 Mm.406408
RefSeq NM_001163440 NM_001163441 NM_008619 XM_006501100 XM_006501101
OMIM
CCDS CCDS38579 CCDS51033
HPRD
IMGT
MGI ID MGI:97054
MGI Symbol Mov10
EMBL AC171110
GenPept
RNA Seq Atlas 17454

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca