Version 5.4
Homo sapiens Gene: SERPINA4
Summary
InnateDB Gene IDBG-18320.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SERPINA4
Gene Name serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
Synonyms KAL; kallistatin; KLST; KST; PI-4; PI4
Species Homo sapiens
Ensembl Gene ENSG00000100665
Encoded Proteins
IDBP-18322
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
IDBP-598235
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
IDBP-601978
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 14:94561091-94569913
Strand Forward strand
Band q32.13
Transcripts
ENST00000298841 ENSP00000298841
ENST00000557004 ENSP00000450838
ENST00000555095 ENSP00000451172
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
Experimentally validated
Total 23 [view]
Protein-Protein 22 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004867 serine-type endopeptidase inhibitor activity
Biological Process
GO:0010951 negative regulation of endopeptidase activity
GO:0030162 regulation of proteolysis
Cellular Component
GO:0005615 extracellular space
GO:0070062 extracellular vesicular exosome
Orthologs
No orthologs found for this gene
Cross-References
SwissProt P29622
TrEMBL A0A024R6I9
UniProt Splice Variant
Entrez Gene 5267
UniGene Hs.609008 Hs.719893
RefSeq NM_001289032 NM_001289033 NM_006215
HUGO HGNC:8948
OMIM 147935
CCDS CCDS9927
HPRD
IMGT
EMBL BC014992 BX248009 BX248760 CH471061 L19684 L28101
GenPept AAA59454 AAC41706 AAH14992 CAD62337 CAD66567 EAW81579 EAW81580 EAW81581
RNA Seq Atlas 5267

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca