Homo sapiens Gene: RPL37
Summary
InnateDB Gene IDBG-18329.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RPL37
Gene Name ribosomal protein L37
Synonyms L37;
Species Homo sapiens
Ensembl Gene ENSG00000145592
Encoded Proteins
ribosomal protein L37
ribosomal protein L37
ribosomal protein L37
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L37E family of ribosomal proteins. It is located in the cytoplasm. The protein contains a C2C2-type zinc finger-like motif. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:40825262-40835335
Strand Reverse strand
Band p13.1
Transcripts
ENST00000274242 ENSP00000274242
ENST00000511787
ENST00000509877 ENSP00000422823
ENST00000507642
ENST00000504562
ENST00000508493 ENSP00000426449
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
Experimentally validated
Total 17 [view]
Protein-Protein 14 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
GO:0046872 metal ion binding
Biological Process
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0006412 translation
GO:0006413 translational initiation
GO:0006414 translational elongation
GO:0006415 translational termination
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
GO:0010467 gene expression
GO:0016032 viral process
GO:0016070 RNA metabolic process
GO:0016071 mRNA metabolic process
GO:0019058 viral life cycle
GO:0019083 viral transcription
GO:0044267 cellular protein metabolic process
Cellular Component
GO:0005622 intracellular
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Eukaryotic Translation Initiation pathway
Influenza Infection pathway
SRP-dependent cotranslational protein targeting to membrane pathway
Nonsense-Mediated Decay (NMD) pathway
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) pathway
Formation of a pool of free 40S subunits pathway
Influenza Viral RNA Transcription and Replication pathway
Translation pathway
Eukaryotic Translation Termination pathway
Metabolism of proteins pathway
Cap-dependent Translation Initiation pathway
Eukaryotic Translation Elongation pathway
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) pathway
Influenza Life Cycle pathway
GTP hydrolysis and joining of the 60S ribosomal subunit pathway
Viral mRNA Translation pathway
Peptide chain elongation pathway
L13a-mediated translational silencing of Ceruloplasmin expression pathway
Gene Expression pathway
Disease pathway
KEGG
Ribosome pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.668276 Hs.731513 Hs.733418 Hs.80545
RefSeq NM_000997
HUGO
OMIM
CCDS CCDS3934
HPRD 16047
IMGT
EMBL
GenPept
RNA Seq Atlas