Version 5.4
Mus musculus Gene: Mybpc1
Summary
InnateDB Gene IDBG-183668.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mybpc1
Gene Name myosin binding protein C, slow-type
Synonyms 8030451F13Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000020061
Encoded Proteins
IDBP-400549
myosin binding protein C, slow-type
IDBP-400548
myosin binding protein C, slow-type
IDBP-535509
myosin binding protein C, slow-type
IDBP-534353
myosin binding protein C, slow-type
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000196091:
This gene encodes a member of the myosin-binding protein C family. Myosin-binding protein C family members are myosin-associated proteins found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. The encoded protein is the slow skeletal muscle isoform of myosin-binding protein C and plays an important role in muscle contraction by recruiting muscle-type creatine kinase to myosin filaments. Mutations in this gene are associated with distal arthrogryposis type I. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:88518279-88605152
Strand Reverse strand
Band C1
Transcripts
ENSMUST00000121629 ENSMUSP00000112615
ENSMUST00000119185 ENSMUSP00000112699
ENSMUST00000124144
ENSMUST00000153964 ENSMUSP00000122472
ENSMUST00000148205
ENSMUST00000156573 ENSMUSP00000119024
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 18 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005200 structural constituent of cytoskeleton
GO:0005515 protein binding
Biological Process
GO:0006936 muscle contraction
Cellular Component
GO:0005856 cytoskeleton
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000196091
View Gene Order
ENSBTAG00000011392
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_16969
Striated Muscle Contraction pathway
REACT_17044
Muscle contraction pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.147208
RefSeq NM_001252372 NM_175418 XM_006513051 XM_006513058
OMIM
CCDS CCDS48666 CCDS56739
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca