Version 5.4
Mus musculus Gene: Cklf
Summary
InnateDB Gene IDBG-185208.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cklf
Gene Name chemokine-like factor
Synonyms 1700001C14Rik; 1810018M11Rik; C32; CKLF1; Cklf2; CKLF3; CKLF4; CKLF5; Cklf6; HSPC224; UCK-1
Species Mus musculus
Ensembl Gene ENSMUSG00000054400
Encoded Proteins
IDBP-185210
chemokine-like factor
IDBP-185212
chemokine-like factor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000217555:
The product of this gene is a cytokine. Cytokines are small proteins that have an essential role in the immune and inflammatory responses. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 16. The protein encoded by this gene is a potent chemoattractant for neutrophils, monocytes and lymphocytes. It also can stimulate the proliferation of skeletal muscle cells. This protein may play important roles in inflammation and in the regeneration of skeletal muscle. Alternatively spliced transcript variants encoding different isoforms have been identified. Naturally occurring read-through transcription occurs between this locus and the neighboring locus CMTM1 (CKLF-like MARVEL transmembrane domain containing 1).[provided by RefSeq, Feb 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:104250903-104264936
Strand Forward strand
Band D3
Transcripts
ENSMUST00000034342 ENSMUSP00000034342
ENSMUST00000098464 ENSMUSP00000096064
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008009 chemokine activity
Biological Process
GO:0008283 cell proliferation
GO:0030593 neutrophil chemotaxis
GO:0030595 leukocyte chemotaxis
GO:0032940 secretion by cell
GO:0048246 macrophage chemotaxis
GO:0048247 lymphocyte chemotaxis
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000217555
View Gene Order
ENSBTAG00000038858
Not yet available
Cross-References
SwissProt Q9DAS1
TrEMBL
UniProt Splice Variant
Entrez Gene 75458
UniGene Mm.269219 Mm.402029
RefSeq NM_029295 NM_001037841
OMIM
CCDS CCDS40450 CCDS40449
HPRD
IMGT
MGI ID MGI:1922708
MGI Symbol Cklf
EMBL AF401530 AF401531 AK005577 AK046397 AK050112 AK086063 AK156237 AK172265 AY046597 AY047360
GenPept AAK94042 AAK94043 AAL05945 AAL10703 BAB24133 BAC32704 BAC34072 BAC39602 BAE33637 BAE42913
RNA Seq Atlas 75458

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca