|Mus musculus Gene: Pkd2|
|Last Modified||2014-10-13 [Report errors or provide feedback]|
|Gene Name||polycystic kidney disease 2|
|Synonyms||C030034P18Rik; PC2; TRPP2;|
polycystic kidney disease 2
|Useful resources||Stemformatics EHFPI ImmGen|
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000118762:
This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2. [provided by RefSeq, Mar 2011]
|Genomic Location||Chromosome 5:104459450-104505819|
|Number of Interactions||
This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
|UniProt Splice Variant|
|RNA Seq Atlas|