Mus musculus Gene: Sars
Summary
InnateDB Gene IDBG-187342.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sars
Gene Name seryl-aminoacyl-tRNA synthetase
Synonyms Sars1; serRS; Strs;
Species Mus musculus
Ensembl Gene ENSMUSG00000068739
Encoded Proteins
seryl-aminoacyl-tRNA synthetase
seryl-aminoacyl-tRNA synthetase
seryl-aminoacyl-tRNA synthetase
seryl-aminoacyl-tRNA synthetase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000031698:
This gene belongs to the class II amino-acyl tRNA family. The encoded enzyme catalyzes the transfer of L-serine to tRNA (Ser) and is related to bacterial and yeast counterparts. Multiple alternatively spliced transcript variants have been described but the biological validity of all variants is unknown. [provided by RefSeq, Jul 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:108424865-108445209
Strand Reverse strand
Band F3
Transcripts
ENSMUST00000090553 ENSMUSP00000088041
ENSMUST00000102625 ENSMUSP00000099685
ENSMUST00000132467 ENSMUSP00000120879
ENSMUST00000153499 ENSMUSP00000118676
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004828 serine-tRNA ligase activity
GO:0005524 ATP binding
Biological Process
GO:0006418 tRNA aminoacylation for protein translation
GO:0006434 seryl-tRNA aminoacylation
GO:0097056 selenocysteinyl-tRNA(Sec) biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
KEGG
Aminoacyl-tRNA biosynthesis pathway
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Cytosolic tRNA aminoacylation pathway
tRNA Aminoacylation pathway
Gene Expression pathway
KEGG
Aminoacyl-tRNA biosynthesis pathway
INOH
Glycine Serine metabolism pathway
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL Q8C483 Q8CEH3
UniProt Splice Variant
Entrez Gene 20226
UniGene Mm.486568
RefSeq NM_011319 NM_001204979
OMIM
CCDS CCDS17760 CCDS57254
HPRD
IMGT
MGI ID MGI:102809
MGI Symbol Sars
EMBL AK028154 AK082793 AL672200 CH466607
GenPept BAC25781 BAC38623 EDL01969
RNA Seq Atlas 20226