Version 5.4
Mus musculus Gene: Meaf6
Summary
InnateDB Gene IDBG-187451.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Meaf6
Gene Name MYST/Esa1-associated factor 6
Synonyms 2310005N01Rik; 2810036M01Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000028863
Encoded Proteins
IDBP-187453
MYST/Esa1-associated factor 6
IDBP-269326
MYST/Esa1-associated factor 6
IDBP-533916
MYST/Esa1-associated factor 6
IDBP-788285
MYST/Esa1-associated factor 6
IDBP-788286
MYST/Esa1-associated factor 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000163875:
This gene encodes a nuclear protein involved in transcriptional activation. The encoded protein may form a component of several different histone acetyltransferase complexes. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:125085134-125113238
Strand Forward strand
Band D2.2
Transcripts
ENSMUST00000055213 ENSMUSP00000053543
ENSMUST00000106171 ENSMUSP00000101777
ENSMUST00000154689 ENSMUSP00000122288
ENSMUST00000124154
ENSMUST00000152816
ENSMUST00000155212
ENSMUST00000184205 ENSMUSP00000138973
ENSMUST00000184118 ENSMUSP00000139156
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 19 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0043968 histone H2A acetylation
GO:0043981 histone H4-K5 acetylation
GO:0043982 histone H4-K8 acetylation
GO:0043983 histone H4-K12 acetylation
GO:0044154 histone H3-K14 acetylation
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0035267 NuA4 histone acetyltransferase complex
GO:0070776 MOZ/MORF histone acetyltransferase complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000163875
View Gene Order
ENSBTAG00000010506
Not yet available
Pathways
NETPATH
REACTOME
REACT_218274
Chromatin organization pathway
REACT_226917
HATs acetylate histones pathway
REACT_202766
Chromatin modifying enzymes pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_172610
HATs acetylate histones pathway
REACT_172623
Chromatin organization pathway
REACT_172633
Chromatin modifying enzymes pathway
REACT_207632
Chromatin organization pathway
REACT_219482
HATs acetylate histones pathway
REACT_227044
Chromatin modifying enzymes pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001290701 NM_027310 XM_006503383
OMIM
CCDS CCDS18637 CCDS71467
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca