Version 5.4
Homo sapiens Gene: CHAF1A
Summary
InnateDB Gene IDBG-18900.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CHAF1A
Gene Name chromatin assembly factor 1, subunit A (p150)
Synonyms CAF-1; CAF1; CAF1B; CAF1P150; P150
Species Homo sapiens
Ensembl Gene ENSG00000167670
Encoded Proteins
IDBP-18904
chromatin assembly factor 1, subunit A (p150)
IDBP-760928
IDBP-764441
IDBP-759800
IDBP-765007
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Chromatin assembly factor I (CAF1) is a nuclear complex consisting of p50, p60 (CHAF1B; MIM 601245), and p150 (CHAF1A) subunits that assembles histone octamers onto replicating DNA in vitro (Kaufman et al., 1995 [PubMed 7600578]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:4402662-4445018
Strand Forward strand
Band p13.3
Transcripts
ENST00000301280 ENSP00000301280
ENST00000587739 ENSP00000467296
ENST00000587580
ENST00000585854 ENSP00000465142
ENST00000587368
ENST00000585371 ENSP00000466888
ENST00000589648 ENSP00000466475
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 106 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 106 [view]
Protein-Protein 106 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003682 chromatin binding
GO:0005515 protein binding
GO:0042802 identical protein binding
GO:0051082 unfolded protein binding
GO:0070087 chromo shadow domain binding
Biological Process
GO:0006260 DNA replication
GO:0006281 DNA repair
GO:0006335 DNA replication-dependent nucleosome assembly
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006461 protein complex assembly
GO:0007049 cell cycle
GO:0031497 chromatin assembly
Cellular Component
GO:0000790 nuclear chromatin
GO:0033186 CAF-1 complex
GO:0043234 protein complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000002835
View Gene Order
ENSBTAG00000008181
Not yet available
Pathways
NETPATH
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.735773 Hs.79018
RefSeq NM_005483
HUGO
OMIM
CCDS CCDS32875
HPRD 03148
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca