Version 5.4
Mus musculus Gene: Nfe2
Summary
InnateDB Gene IDBG-189502.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nfe2
Gene Name nuclear factor, erythroid derived 2
Synonyms NF-E2; p45; p45nf-e2; p45NFE2
Species Mus musculus
Ensembl Gene ENSMUSG00000058794
Encoded Proteins
IDBP-189504
nuclear factor, erythroid derived 2
IDBP-534536
nuclear factor, erythroid derived 2
IDBP-532520
nuclear factor, erythroid derived 2
IDBP-537925
nuclear factor, erythroid derived 2
IDBP-537513
nuclear factor, erythroid derived 2
IDBP-532640
nuclear factor, erythroid derived 2
IDBP-540885
nuclear factor, erythroid derived 2
IDBP-540596
nuclear factor, erythroid derived 2
IDBP-535885
nuclear factor, erythroid derived 2
IDBP-536100
nuclear factor, erythroid derived 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000123405:
Gene Information
Type Protein coding
Genomic Location Chromosome 15:103248212-103258403
Strand Reverse strand
Band F3
Transcripts
ENSMUST00000075192 ENSMUSP00000074684
ENSMUST00000133600 ENSMUSP00000121817
ENSMUST00000156927 ENSMUSP00000114160
ENSMUST00000149111 ENSMUSP00000122476
ENSMUST00000134554 ENSMUSP00000117474
ENSMUST00000134193 ENSMUSP00000123064
ENSMUST00000131364 ENSMUSP00000116158
ENSMUST00000132836 ENSMUSP00000120256
ENSMUST00000154510 ENSMUSP00000116678
ENSMUST00000132438 ENSMUSP00000116079
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 78 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Experimentally validated
Total 78 [view]
Protein-Protein 75 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 18 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
GO:0047485 protein N-terminus binding
GO:0050699 WW domain binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007267 cell-cell signaling
GO:0030502 negative regulation of bone mineralization
GO:0034242 negative regulation of syncytium formation by plasma membrane fusion
GO:0060716 labyrinthine layer blood vessel development
GO:2000758 positive regulation of peptidyl-lysine acetylation
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0015629 actin cytoskeleton
GO:0016605 PML body
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000123405
View Gene Order
ENSBTAG00000001562
Not yet available
Pathways
NETPATH
REACTOME
REACT_224553
Hemostasis pathway
REACT_198649
Factors involved in megakaryocyte development and platelet production pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_24970
Factors involved in megakaryocyte development and platelet production pathway
REACT_604
Hemostasis pathway
REACT_215067
Factors involved in megakaryocyte development and platelet production pathway
REACT_212196
Hemostasis pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.403160 Mm.457989
RefSeq NM_008685 XM_006520569 XM_006520571 XM_006520573 XM_006520574 XM_006520575
OMIM
CCDS CCDS27900
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca