Version 5.4
Mus musculus Gene: Tfeb
Summary
InnateDB Gene IDBG-189516.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tfeb
Gene Name transcription factor EB
Synonyms bHLHe35; Tcfeb
Species Mus musculus
Ensembl Gene ENSMUSG00000023990
Encoded Proteins
IDBP-189518
transcription factor EB
IDBP-189520
transcription factor EB
IDBP-254203
transcription factor EB
IDBP-254207
transcription factor EB
IDBP-535436
transcription factor EB
IDBP-532157
transcription factor EB
IDBP-540355
transcription factor EB
IDBP-536672
transcription factor EB
IDBP-539243
transcription factor EB
IDBP-537366
transcription factor EB
IDBP-539873
transcription factor EB
IDBP-540720
transcription factor EB
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000112561:
Gene Information
Type Protein coding
Genomic Location Chromosome 17:47737030-47792419
Strand Forward strand
Band C
Transcripts
ENSMUST00000086932 ENSMUSP00000084151
ENSMUST00000024786 ENSMUSP00000024786
ENSMUST00000113288 ENSMUSP00000108913
ENSMUST00000113284 ENSMUSP00000108909
ENSMUST00000126258 ENSMUSP00000119442
ENSMUST00000137845 ENSMUSP00000119508
ENSMUST00000125177 ENSMUSP00000121888
ENSMUST00000130208 ENSMUSP00000122228
ENSMUST00000159641 ENSMUSP00000124379
ENSMUST00000160373 ENSMUSP00000124708
ENSMUST00000141631 ENSMUSP00000118057
ENSMUST00000146782 ENSMUSP00000120311
ENSMUST00000124765
ENSMUST00000162719
ENSMUST00000140715
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 2 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0044212 transcription regulatory region DNA binding
GO:0046982 protein heterodimerization activity
GO:0046983 protein dimerization activity
Biological Process
GO:0001892 embryonic placenta development
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006914 autophagy
GO:0006959 humoral immune response
GO:0007040 lysosome organization
GO:0010508 positive regulation of autophagy
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription factor complex
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000112561
View Gene Order
ENSBTAG00000012384
Not yet available
Cross-References
SwissProt
TrEMBL D3Z219
UniProt Splice Variant
Entrez Gene 21425
UniGene Mm.2305
RefSeq NM_001161722 NM_001161723 NM_011549 XM_006524002 XM_006524003 XM_006524005 XM_006524006 XM_006524007 XM_006524008
OMIM
CCDS CCDS28856 CCDS50133
HPRD
IMGT
MGI ID MGI:103270
MGI Symbol Tfeb
EMBL AC113536 AC124830
GenPept
RNA Seq Atlas 21425

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca