Version 5.4
| Mus musculus Gene: Clec1b | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-191926.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Clec1b | ||||||||
| Gene Name | C-type lectin domain family 1, member b | ||||||||
| Synonyms | 1810061I13Rik; Clec-2; Clec2 | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000030159 | ||||||||
| Encoded Proteins |
C-type lectin domain family 1, member b
C-type lectin domain family 1, member b
C-type lectin domain family 1, member b
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| InnateDB Annotation | |||||||||
| Summary |
Clec1b is expressed in myeloid cells and acts as a Syk-coupled C-type lectin receptor (CLR) able to modulate Toll-like receptor (TLR) signaling and inflammatory responses.
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| InnateDB Annotation from Orthologs | |||||||||
| Summary |
[Homo sapiens] CLEC1B is expressed in myeloid cells and acts as a SYK-coupled C-type lectin receptor (CLR) able to modulate Toll-like receptor (TLR) signaling and inflammatory responses. ( Demonstrated in murine model)
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| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000165682:
Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1; MIM 602894) and NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells (Colonna et al., 2000 [PubMed 10671229]).[supplied by OMIM, Jan 2011] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 6:129397297-129409335 | ||||||||
| Strand | Forward strand | ||||||||
| Band | F3 | ||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Cross-References | |||||||||
| SwissProt | Q9JL99 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 56760 | ||||||||
| UniGene | Mm.30700 | ||||||||
| RefSeq | NM_001204239 NM_001204253 NM_019985 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS57452 CCDS20586 CCDS57453 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | MGI:1913287 | ||||||||
| MGI Symbol | Clec1b | ||||||||
| EMBL | AF201457 BC064054 EF070191 | ||||||||
| GenPept | AAF36831 AAH64054 ABK60036 | ||||||||
| RNA Seq Atlas | 56760 | ||||||||