Homo sapiens Gene: BRSK2
Summary
InnateDB Gene IDBG-19235.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BRSK2
Gene Name BR serine/threonine kinase 2
Synonyms C11orf7; PEN11B; SAD1; SADA; STK29;
Species Homo sapiens
Ensembl Gene ENSG00000174672
Encoded Proteins
BR serine/threonine kinase 2
BR serine/threonine kinase 2
BR serine/threonine kinase 2
BR serine/threonine kinase 2
BR serine/threonine kinase 2
BR serine/threonine kinase 2
BR serine/threonine kinase 2
BR serine/threonine kinase 2
BR serine/threonine kinase 2
BR serine/threonine kinase 2
BR serine/threonine kinase 2
BR serine/threonine kinase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 11:1389899-1462689
Strand Forward strand
Band p15.5
Transcripts
ENST00000308219 ENSP00000310697
ENST00000382179 ENSP00000371614
ENST00000529433 ENSP00000433684
ENST00000528841 ENSP00000432000
ENST00000531197 ENSP00000431152
ENST00000526678 ENSP00000433370
ENST00000528596 ENSP00000434075
ENST00000524702 ENSP00000432672
ENST00000528710 ENSP00000433235
ENST00000529951 ENSP00000432252
ENST00000531078
ENST00000533606 ENSP00000436474
ENST00000526768
ENST00000531932
ENST00000544817 ENSP00000445168
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0019901 protein kinase binding
GO:0050321 tau-protein kinase activity
Biological Process
GO:0000086 G2/M transition of mitotic cell cycle
GO:0006468 protein phosphorylation
GO:0006887 exocytosis
GO:0007067 mitotic nuclear division
GO:0007409 axonogenesis
GO:0016310 phosphorylation
GO:0018105 peptidyl-serine phosphorylation
GO:0030010 establishment of cell polarity
GO:0030182 neuron differentiation
GO:0031532 actin cytoskeleton reorganization
GO:0048812 neuron projection morphogenesis
GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
Cellular Component
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005813 centrosome
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
REACTOME
KEGG
INOH
PID BIOCARTA
PID NCI
LKB1 signaling events
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.170819
RefSeq NM_001256627 NM_001256629 NM_001256630 NM_001282218 NM_003957 XM_006718374 XM_006718375
HUGO
OMIM
CCDS CCDS41590 CCDS58106 CCDS58107 CCDS58108 CCDS60696
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas