Version 5.4
Mus musculus Gene: Ddx19b
Summary
InnateDB Gene IDBG-192742.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ddx19b
Gene Name DEAD (Asp-Glu-Ala-Asp) box polypeptide 19b
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000033658
Encoded Proteins
IDBP-192744
DEAD (Asp-Glu-Ala-Asp) box polypeptide 19b
IDBP-192746
DEAD (Asp-Glu-Ala-Asp) box polypeptide 19b
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000157349:
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which exhibits RNA-dependent ATPase and ATP-dependent RNA-unwinding activities. This protein is recruited to the cytoplasmic fibrils of the nuclear pore complex, where it participates in the export of mRNA from the nucleus. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:111003188-111031751
Strand Reverse strand
Band E1
Transcripts
ENSMUST00000040241 ENSMUSP00000038551
ENSMUST00000065784 ENSMUSP00000066806
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.
Predicted by orthology
Total 19 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003676 nucleic acid binding
GO:0004386 helicase activity
GO:0005524 ATP binding
Biological Process
GO:0008150 biological_process
GO:0008152 metabolic process
Cellular Component
GO:0005635 nuclear envelope
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000157349
View Gene Order
ENSBTAG00000020714
Not yet available
Cross-References
SwissProt
TrEMBL Q8BZY3 Q8R3C7
UniProt Splice Variant
Entrez Gene 234733
UniGene Mm.418590 Mm.421084 Mm.436464 Mm.482176
RefSeq NM_001190786 NM_001190800 NM_172284
OMIM
CCDS CCDS22669 CCDS57645
HPRD
IMGT
MGI ID MGI:2148251
MGI Symbol Ddx19b
EMBL AC093451 AK033235 AK147499 BC025594 CH466525
GenPept AAH25594 BAC28204 BAE27953 EDL11481
RNA Seq Atlas 234733

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca