InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Avpr1a

Summary

InnateDB Gene

IDBG-193300.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Avpr1a

Gene Name

arginine vasopressin receptor 1A

Synonyms

AVPR; Avpr1; V1a; V1aR

Species

Mus musculus

Ensembl Gene

ENSMUSG00000020123

Encoded Proteins

IDBP-193302

arginine vasopressin receptor 1A

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene encodes a receptor for arginine vasopressin, a neurohypophyseal hormone involved in diuresis inhibition, smooth muscle contraction, liver glycogenolysis stimulation and regulation of adrenocorticotropic hormone release from the pituitary. This receptor represents one of three G protein-coupled arginine vasopressin receptors which functions through a phosphotidylinositol-calcium second messenger system in vascular and hepatic tissues [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 10:122448499-122453453

Strand

Forward strand

Band

Transcripts

ENSMUST00000020323

ENSMUSP00000020323

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004930	G-protein coupled receptor activity
GO:0005000	vasopressin receptor activity
GO:0005515	protein binding
GO:0017046	peptide hormone binding
GO:0031894	V1A vasopressin receptor binding

Biological Process

GO:0001992	regulation of systemic arterial blood pressure by vasopressin
GO:0002125	maternal aggressive behavior
GO:0003084	positive regulation of systemic arterial blood pressure
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007204	positive regulation of cytosolic calcium ion concentration
GO:0007621	negative regulation of female receptivity
GO:0007625	grooming behavior
GO:0008284	positive regulation of cell proliferation
GO:0010033	response to organic substance
GO:0010035	response to inorganic substance
GO:0010460	positive regulation of heart rate
GO:0014049	positive regulation of glutamate secretion
GO:0014902	myotube differentiation
GO:0019722	calcium-mediated signaling
GO:0021537	telencephalon development
GO:0030307	positive regulation of cell growth
GO:0031394	positive regulation of prostaglandin biosynthetic process
GO:0032849	positive regulation of cellular pH reduction
GO:0035176	social behavior
GO:0035815	positive regulation of renal sodium excretion
GO:0042631	cellular response to water deprivation
GO:0042711	maternal behavior
GO:0042713	sperm ejaculation
GO:0043084	penile erection
GO:0045777	positive regulation of blood pressure
GO:0045907	positive regulation of vasoconstriction
GO:0051412	response to corticosterone
GO:0051970	negative regulation of transmission of nerve impulse