Mus musculus Gene: Emr1
Summary
InnateDB Gene IDBG-194190.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Emr1
Gene Name EGF-like module containing, mucin-like, hormone receptor-like sequence 1
Synonyms DD7A5-7; EGF-TM7; F4/80; Gpf480; Ly71; TM7LN3;
Species Mus musculus
Ensembl Gene ENSMUSG00000004730
Encoded Proteins
EGF-like module containing, mucin-like, hormone receptor-like sequence 1
EGF-like module containing, mucin-like, hormone receptor-like sequence 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000174837:
This gene encodes a protein that has a domain resembling seven transmembrane G protein-coupled hormone receptors (7TM receptors) at its C-terminus. The N-terminus of the encoded protein has six EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:57358686-57483529
Strand Forward strand
Band D
Transcripts
ENSMUST00000086763 ENSMUSP00000083971
ENSMUST00000004850 ENSMUSP00000004850
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 2 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004888 transmembrane signaling receptor activity
GO:0004930 G-protein coupled receptor activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007218 neuropeptide signaling pathway
Cellular Component
GO:0009897 external side of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0071944 cell periphery
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Signaling by GPCR pathway
Signal Transduction pathway
GPCR ligand binding pathway
Class B/2 (Secretin family receptors) pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q61549
TrEMBL Q3S4B0 Q3U9R0 Q6LCD7
UniProt Splice Variant
Entrez Gene 13733
UniGene Mm.2254
RefSeq NM_010130 XM_006523601 XM_006523602
OMIM
CCDS CCDS50160
HPRD
IMGT
MGI ID MGI:106912
MGI Symbol Emr1
EMBL AK133202 AK151682 BC075688 DQ167573 U66888 U66889 X93328
GenPept AAC53184 AAC53185 AAH75688 ABA02180 BAE21555 BAE30606 CAA63720
RNA Seq Atlas 13733