Homo sapiens Gene: PRR4
Summary
InnateDB Gene IDBG-19535.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PRR4
Gene Name proline rich 4 (lacrimal)
Synonyms LPRP; PROL4;
Species Homo sapiens
Ensembl Gene ENSG00000111215
Encoded Proteins
proline rich 4 (lacrimal)
proline-rich protein HaeIII subfamily 1
proline rich 4 (lacrimal)
proline-rich protein HaeIII subfamily 1
proline rich 4 (lacrimal)
proline rich 4 (lacrimal)
proline-rich protein HaeIII subfamily 1
proline-rich protein HaeIII subfamily 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This locus represents naturally occurring read-through transcription between the neighboring PRH1 (proline-rich protein HaeIII subfamily 1) and PRR4 (proline rich 4, lacrimal) genes on chromosome 12. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is thus unlikely to produce a protein product. [provided by RefSeq, Feb 2011] This gene encodes a member of the proline-rich protein family that lacks a conserved repetitive domain. This protein may play a role in protective functions in the eye. Alternative splicing result in multiple transcript variants. Read-through transcription also exists between this gene and the upstream PRH1 (proline-rich protein HaeIII subfamily 1) gene. [provided by RefSeq, Feb 2011]
This gene encodes a member of the proline-rich protein family that lacks a conserved repetitive domain. This protein may play a role in protective functions in the eye. Alternative splicing result in multiple transcript variants. Read-through transcription also exists between this gene and the upstream PRH1 (proline-rich protein HaeIII subfamily 1) gene. [provided by RefSeq, Feb 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:10845849-11171613
Strand Reverse strand
Band p13.2
Transcripts
ENST00000228811 ENSP00000228811
ENST00000538332 ENSP00000481761
ENST00000542881
ENST00000544994 ENSP00000438046
ENST00000536668 ENSP00000482961
ENST00000535024 ENSP00000481571
ENST00000540107 ENSP00000443939
ENST00000539285
ENST00000539179
ENST00000540808
ENST00000542658
ENST00000539853 ENSP00000482068
ENST00000543626 ENSP00000479168
ENST00000541977
ENST00000536086
ENST00000546317
ENST00000534923
ENST00000541456
ENST00000546265
ENST00000541175
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0001895 retina homeostasis
GO:0007601 visual perception
Cellular Component
GO:0005615 extracellular space
Orthologs
No orthologs found for this gene
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001291314 NM_006250 NM_007244 NM_001098538
HUGO
OMIM
CCDS CCDS41756 CCDS55804
HPRD 09248
IMGT
EMBL
GenPept
RNA Seq Atlas