Mus musculus Gene: Recql
Summary
InnateDB Gene IDBG-196785.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Recql
Gene Name RecQ protein-like
Synonyms RecQ1;
Species Mus musculus
Ensembl Gene ENSMUSG00000030243
Encoded Proteins
RecQ protein-like
RecQ protein-like
RecQ protein-like
RecQ protein-like
RecQ protein-like
RecQ protein-like
RecQ protein-like
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000004700:
The protein encoded by this gene is a member of the RecQ DNA helicase family. DNA helicases are enzymes involved in various types of DNA repair, including mismatch repair, nucleotide excision repair and direct repair. Some members of this family are associated with genetic disorders with predisposition to malignancy and chromosomal instability. The biological function of this helicase has not yet been determined. Two alternatively spliced transcripts, which encode the same isoform but differ in their 5' and 3' UTRs, have been described. [provided by RefSeq, Jul 2008]
The protein encoded by this gene is a member of the RecQ DNA helicase family. DNA helicases are enzymes involved in various types of DNA repair, including mismatch repair, nucleotide excision repair and direct repair. Some members of this family are associated with genetic disorders with predisposition to malignancy and chromosomal instability. The biological function of this helicase has not yet been determined. Two alternatively spliced transcripts, which encode the same isoform but differ in their 5\' and 3\' UTRs, have been described. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:142350342-142387087
Strand Reverse strand
Band G2
Transcripts
ENSMUST00000032370 ENSMUSP00000032370
ENSMUST00000100832 ENSMUSP00000098394
ENSMUST00000111803 ENSMUSP00000107434
ENSMUST00000141504 ENSMUSP00000119452
ENSMUST00000138578
ENSMUST00000123912 ENSMUSP00000122409
ENSMUST00000154870
ENSMUST00000155149
ENSMUST00000143102
ENSMUST00000129694 ENSMUSP00000122328
ENSMUST00000128082 ENSMUSP00000120951
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0004386 helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008026 ATP-dependent helicase activity
GO:0036310 annealing helicase activity
GO:0043140 ATP-dependent 3'-5' DNA helicase activity
Biological Process
GO:0000733 DNA strand renaturation
GO:0006200 ATP catabolic process
GO:0006260 DNA replication
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0032508 DNA duplex unwinding
Cellular Component
GO:0005634 nucleus
GO:0015630 microtubule cytoskeleton
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 19691
UniGene Mm.27407
RefSeq NM_001204906 NM_001204907 NM_023042 XM_006506926 XM_006506927
OMIM
CCDS CCDS39695 CCDS57465 CCDS57466
HPRD
IMGT
MGI ID MGI:103021
MGI Symbol Recql
EMBL
GenPept
RNA Seq Atlas 19691