Version 5.4
Mus musculus Gene: Brap
Summary
InnateDB Gene IDBG-197596.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Brap
Gene Name BRCA1 associated protein
Synonyms 3010002G07Rik; BRAP2; IMP
Species Mus musculus
Ensembl Gene ENSMUSG00000029458
Encoded Proteins
IDBP-197598
BRCA1 associated protein
IDBP-257429
BRCA1 associated protein
IDBP-542662
BRCA1 associated protein
IDBP-541685
BRCA1 associated protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000089234:
The protein encoded by this gene was identified by its ability to bind to the nuclear localization signal of BRCA1 and other proteins. It is a cytoplasmic protein which may regulate nuclear targeting by retaining proteins with a nuclear localization signal in the cytoplasm. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:121660563-121687248
Strand Forward strand
Band F
Transcripts
ENSMUST00000031414 ENSMUSP00000031414
ENSMUST00000111765 ENSMUSP00000107395
ENSMUST00000140996 ENSMUSP00000122536
ENSMUST00000132491
ENSMUST00000142701
ENSMUST00000148052
ENSMUST00000127703 ENSMUSP00000118574
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 26 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 26 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0008139 nuclear localization sequence binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0000165 MAPK cascade
GO:0007265 Ras protein signal transduction
GO:0009968 negative regulation of signal transduction
GO:0016567 protein ubiquitination
Cellular Component
GO:0000151 ubiquitin ligase complex
GO:0005737 cytoplasm
GO:0031965 nuclear membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000089234
View Gene Order
ENSBTAG00000001168
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.415675
RefSeq NM_001289543 NM_001289544 NM_028227 XM_006530469
OMIM
CCDS CCDS19640
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca