Version 5.4
Mus musculus Gene: P2rx5
Summary
InnateDB Gene IDBG-197834.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol P2rx5
Gene Name purinergic receptor P2X, ligand-gated ion channel, 5
Synonyms P2X5
Species Mus musculus
Ensembl Gene ENSMUSG00000005950
Encoded Proteins
IDBP-197836
purinergic receptor P2X, ligand-gated ion channel, 5
IDBP-535766
purinergic receptor P2X, ligand-gated ion channel, 5
IDBP-532770
purinergic receptor P2X, ligand-gated ion channel, 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000083454:
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream gene, TAX1BP3 (Tax1 binding protein 3). [provided by RefSeq, Mar 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:73160421-73172685
Strand Forward strand
Band B4
Transcripts
ENSMUST00000006104 ENSMUSP00000006104
ENSMUST00000135202 ENSMUSP00000118448
ENSMUST00000136894 ENSMUSP00000121834
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001614 purinergic nucleotide receptor activity
GO:0004931 extracellular ATP-gated cation channel activity
GO:0005216 ion channel activity
GO:0005524 ATP binding
Biological Process
GO:0006811 ion transport
GO:0006812 cation transport
GO:0007166 cell surface receptor signaling pathway
GO:0034220 ion transmembrane transport
GO:0035590 purinergic nucleotide receptor signaling pathway
Cellular Component
GO:0005639 integral component of nuclear inner membrane
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000083454
View Gene Order
ENSBTAG00000015258
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu04020
Calcium signaling pathway pathway
mmu04080
Neuroactive ligand-receptor interaction pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04080
Neuroactive ligand-receptor interaction pathway
hsa04020
Calcium signaling pathway pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.156893
RefSeq NM_033321
OMIM
CCDS CCDS24998
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca