Version 5.4
Mus musculus Gene: Dlg2
Summary
InnateDB Gene IDBG-198905.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dlg2
Gene Name discs, large homolog 2 (Drosophila)
Synonyms A330103J02Rik; B230218P12Rik; B330007M19Rik; Dlgh2; Gm1197; PSD93
Species Mus musculus
Ensembl Gene ENSMUSG00000052572
Encoded Proteins
IDBP-198907
discs, large homolog 2 (Drosophila)
IDBP-198909
discs, large homolog 2 (Drosophila)
IDBP-267180
discs, large homolog 2 (Drosophila)
IDBP-267182
discs, large homolog 2 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000150672:
This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. The encoded protein forms a heterodimer with a related family member that may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described, but their full-length nature is not known. [provided by RefSeq, Dec 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:91090706-92447003
Strand Forward strand
Band E1
Transcripts
ENSMUST00000074273 ENSMUSP00000073885
ENSMUST00000098308 ENSMUSP00000095910
ENSMUST00000107196 ENSMUSP00000102814
ENSMUST00000107193 ENSMUSP00000102811
ENSMUST00000146563
ENSMUST00000152139
ENSMUST00000128592
ENSMUST00000129818
ENSMUST00000138389
ENSMUST00000135581
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.
Experimentally validated
Total 15 [view]
Protein-Protein 14 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 25 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007268 synaptic transmission
GO:0010923 negative regulation of phosphatase activity
GO:0019233 sensory perception of pain
Cellular Component
GO:0014069 postsynaptic density
GO:0030054 cell junction
GO:0044224 juxtaparanode region of axon
GO:0045211 postsynaptic membrane
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000150672
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.257035 Mm.397161 Mm.466200
RefSeq NM_001243046 NM_011807 XM_006507767 XM_006507768 XM_006507769 XM_006507770 XM_006507771 XM_006507773 XM_006507774 XM_006507775 XM_006507776 XM_006507777 XM_006507778 XM_006507779 XM_006507780 XM_006507781 XM_006507782 XM_006507783 XM_006507784 XM_006507785 XM_006507786 XM_006507791
OMIM
CCDS CCDS40021 CCDS57562
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca