Version 5.4
Homo sapiens Gene: TBL2
Summary
InnateDB Gene IDBG-19962.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TBL2
Gene Name transducin (beta)-like 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000106638
Encoded Proteins
IDBP-19964
transducin (beta)-like 2
IDBP-377589
transducin (beta)-like 2
IDBP-377592
transducin (beta)-like 2
IDBP-377595
transducin (beta)-like 2
IDBP-377596
transducin (beta)-like 2
IDBP-377600
transducin (beta)-like 2
IDBP-377602
transducin (beta)-like 2
IDBP-377610
transducin (beta)-like 2
IDBP-377614
transducin (beta)-like 2
IDBP-377618
transducin (beta)-like 2
IDBP-377619
transducin (beta)-like 2
IDBP-806612
transducin (beta)-like 2
IDBP-806618
transducin (beta)-like 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the beta-transducin protein family. Most proteins of the beta-transducin family are involved in regulatory functions. This protein is possibly involved in some intracellular signaling pathway. This gene is deleted in Williams-Beuren syndrome, a developmental disorder caused by deletion of multiple genes at 7q11.23. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:73568932-73578791
Strand Reverse strand
Band q11.23
Transcripts
ENST00000305632 ENSP00000307260
ENST00000450285 ENSP00000409820
ENST00000424598 ENSP00000398195
ENST00000417008 ENSP00000407503
ENST00000432538 ENSP00000413979
ENST00000433464 ENSP00000404242
ENST00000426966 ENSP00000410737
ENST00000452475
ENST00000437521 ENSP00000400569
ENST00000435792 ENSP00000408255
ENST00000452125 ENSP00000414865
ENST00000458466 ENSP00000406418
ENST00000459913
ENST00000488915
ENST00000495885
ENST00000476136
ENST00000479892 ENSP00000480898
ENST00000465279
ENST00000496056
ENST00000469518
ENST00000468669
ENST00000610724 ENSP00000484750
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 25 experimentally validated interaction(s) in this database.
Experimentally validated
Total 25 [view]
Protein-Protein 25 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000005374
View Gene Order
ENSBTAG00000000321
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.647044
RefSeq NM_012453
HUGO
OMIM
CCDS CCDS5551
HPRD 09319
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca