Version 5.4
Mus musculus Gene: Ndufaf1
Summary
InnateDB Gene IDBG-199821.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ndufaf1
Gene Name NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1
Synonyms 2410001M24Rik; CGI-65; CIA30
Species Mus musculus
Ensembl Gene ENSMUSG00000027305
Encoded Proteins
IDBP-199823
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1
IDBP-259475
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1
IDBP-259477
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000137806:
This gene encodes a complex I assembly factor protein. Complex I (NADH-ubiquinone oxidoreductase) catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q) in the first step of the mitochondrial respiratory chain, resulting in the translocation of protons across the inner mitochondrial membrane. The encoded protein is required for assembly of complex I, and mutations in this gene are a cause of mitochondrial complex I deficiency. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 19. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:119655446-119662827
Strand Reverse strand
Band E5
Transcripts
ENSMUST00000028768 ENSMUSP00000028768
ENSMUST00000110802 ENSMUSP00000106426
ENSMUST00000110801 ENSMUSP00000106425
ENSMUST00000154127
ENSMUST00000131596
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
GO:0008810 cellulase activity
Biological Process
GO:0008150 biological_process
GO:0030245 cellulose catabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000137806
View Gene Order
ENSBTAG00000010778
Not yet available
Cross-References
SwissProt
TrEMBL A2AQ17
UniProt Splice Variant
Entrez Gene 69702
UniGene Mm.406212 Mm.5390
RefSeq NM_027175 XM_006500148 XM_006500149 XM_006500151
OMIM
CCDS CCDS38207
HPRD
IMGT
MGI ID MGI:1916952
MGI Symbol Ndufaf1
EMBL AL844536
GenPept
RNA Seq Atlas 69702

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca