Mus musculus Gene: Wdr6
Summary
InnateDB Gene IDBG-200295.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Wdr6
Gene Name WD repeat domain 6
Synonyms mWDR6;
Species Mus musculus
Ensembl Gene ENSMUSG00000066357
Encoded Proteins
WD repeat domain 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000178252:
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. The encoded protein interacts with serine/threonine kinase 11, and is implicated in cell growth arrest. [provided by RefSeq, Aug 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:108572313-108578670
Strand Reverse strand
Band F2
Transcripts
ENSMUST00000068700 ENSMUSP00000070927
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0043560 insulin receptor substrate binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0007050 cell cycle arrest
GO:0008285 negative regulation of cell proliferation
GO:0010507 negative regulation of autophagy
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0008180 COP9 signalosome
GO:0043234 protein complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Cross-References
SwissProt Q99ME2
TrEMBL Q8CFV1
UniProt Splice Variant
Entrez Gene 83669
UniGene Mm.335454 Mm.481124
RefSeq NM_031392
OMIM
CCDS CCDS23532
HPRD
IMGT
MGI ID MGI:1930140
MGI Symbol Wdr6
EMBL AF348591 AK037181 AK146617 AK163752 BC035951 BC050894 BC054367 CH466560
GenPept AAH35951 AAH50894 AAH54367 AAK31166 BAC29740 BAE27306 BAE37480 EDL21306
RNA Seq Atlas 83669