Mus musculus Gene: Gemin4
Summary
InnateDB Gene IDBG-200772.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gemin4
Gene Name gem (nuclear organelle) associated protein 4
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000049396
Encoded Proteins
gem (nuclear organelle) associated protein 4
gem (nuclear organelle) associated protein 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000179409:
The product of this gene is part of a large complex localized to the cytoplasm, nucleoli, and to discrete nuclear bodies called Gemini bodies (gems). The complex functions in spliceosomal snRNP assembly in the cytoplasm, and regenerates spliceosomes required for pre-mRNA splicing in the nucleus. The encoded protein directly interacts with a DEAD box protein and several spliceosome core proteins. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:76210571-76217664
Strand Reverse strand
Band B5
Transcripts
ENSMUST00000102500 ENSMUSP00000099558
ENSMUST00000143822 ENSMUSP00000128057
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 54 interaction(s) predicted by orthology.
Predicted by orthology
Total 54 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0000387 spliceosomal snRNP assembly
Cellular Component
GO:0005829 cytosol
GO:0016020 membrane
GO:0032797 SMN complex
GO:0034719 SMN-Sm protein complex
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
RNA transport pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
snRNP Assembly pathway
Metabolism of non-coding RNA pathway
Gene Expression pathway
KEGG
RNA transport pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.468689 Mm.482713
RefSeq NM_177367
OMIM
CCDS CCDS25061
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas