Version 5.4
Mus musculus Gene: Rfwd2
Summary
InnateDB Gene IDBG-200867.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rfwd2
Gene Name ring finger and WD repeat domain 2
Synonyms AI316802; C80879; Cop1
Species Mus musculus
Ensembl Gene ENSMUSG00000040782
Encoded Proteins
IDBP-200869
ring finger and WD repeat domain 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143207:
Gene Information
Type Protein coding
Genomic Location Chromosome 1:159232326-159347580
Strand Forward strand
Band H1
Transcripts
ENSMUST00000076894 ENSMUSP00000076160
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 66 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 66 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0016567 protein ubiquitination
Cellular Component
GO:0000139 Golgi membrane
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005925 focal adhesion
GO:0016607 nuclear speck
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000143207
View Gene Order
ENSBTAG00000031385
Not yet available
Pathways
NETPATH
REACTOME
REACT_212633
Autodegradation of the E3 ubiquitin ligase COP1 pathway
REACT_257943
p53-Dependent G1 DNA Damage Response pathway
REACT_254524
p53-Dependent G1/S DNA damage checkpoint pathway
REACT_188804
Cell Cycle pathway
REACT_256790
Stabilization of p53 pathway
REACT_256025
Cell Cycle Checkpoints pathway
REACT_246312
G1/S DNA Damage Checkpoints pathway
KEGG
mmu04120
Ubiquitin mediated proteolysis pathway
mmu04115
p53 signaling pathway pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_20549
Autodegradation of the E3 ubiquitin ligase COP1 pathway
REACT_309
Stabilization of p53 pathway
REACT_1625
p53-Dependent G1 DNA Damage Response pathway
REACT_85
p53-Dependent G1/S DNA damage checkpoint pathway
REACT_115566
Cell Cycle pathway
REACT_2254
G1/S DNA Damage Checkpoints pathway
REACT_1538
Cell Cycle Checkpoints pathway
KEGG
hsa04120
Ubiquitin mediated proteolysis pathway
hsa04115
p53 signaling pathway pathway
INOH
PID NCI
p53downstreampathway
Direct p53 effectors
p53regulationpathway
p53 pathway
atm_pathway
ATM pathway
Cross-References
SwissProt Q9R1A8
TrEMBL
UniProt Splice Variant
Entrez Gene 26374
UniGene Mm.328135 Mm.394355
RefSeq NM_011931 XM_006496859 XM_006496861
OMIM
CCDS CCDS35745
HPRD
IMGT
MGI ID MGI:1347046
MGI Symbol Rfwd2
EMBL AF151110 BC082804
GenPept AAD51094 AAH82804
RNA Seq Atlas 26374

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca