Mus musculus Gene: Hbb-y
Summary
InnateDB Gene IDBG-203771.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Hbb-y
Gene Name hemoglobin Y, beta-like embryonic chain
Synonyms Ey; Hby;
Species Mus musculus
Ensembl Gene ENSMUSG00000052187
Encoded Proteins
hemoglobin Y, beta-like embryonic chain
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000213931:
The epsilon globin gene (HBE) is normally expressed in the embryonic yolk sac: two epsilon chains together with two zeta chains (an alpha-like globin) constitute the embryonic hemoglobin Hb Gower I; two epsilon chains together with two alpha chains form the embryonic Hb Gower II. Both of these embryonic hemoglobins are normally supplanted by fetal, and later, adult hemoglobin. The five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5'-epsilon - G-gamma - A-gamma - delta - beta-3' [provided by RefSeq, Jul 2008]
The epsilon globin gene (HBE) is normally expressed in the embryonic yolk sac: two epsilon chains together with two zeta chains (an alpha-like globin) constitute the embryonic hemoglobin Hb Gower I; two epsilon chains together with two alpha chains form the embryonic Hb Gower II. Both of these embryonic hemoglobins are normally supplanted by fetal, and later, adult hemoglobin. The five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5\'-epsilon - G-gamma - A-gamma - delta - beta-3\' [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:103851745-103853240
Strand Reverse strand
Band E3
Transcripts
ENSMUST00000033229 ENSMUSP00000033229
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005344 oxygen transporter activity
GO:0005506 iron ion binding
GO:0019825 oxygen binding
GO:0020037 heme binding
GO:0031721 hemoglobin alpha binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0015671 oxygen transport
GO:0051291 protein heterooligomerization
Cellular Component
GO:0005833 hemoglobin complex
GO:0072562 blood microparticle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Factors involved in megakaryocyte development and platelet production pathway
Hemostasis pathway
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL Q9CR49
UniProt Splice Variant
Entrez Gene 15135
UniGene Mm.467549 Mm.467553
RefSeq NM_008221
OMIM
CCDS CCDS21593
HPRD
IMGT
MGI ID MGI:96027
MGI Symbol Hbb-y
EMBL AC131116 AK012501 AK012897 BC057014
GenPept AAH57014 BAB28284 BAB28541
RNA Seq Atlas 15135