Version 5.4
Mus musculus Gene: Taf15
Summary
InnateDB Gene IDBG-205438.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Taf15
Gene Name TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor
Synonyms 2610111C21Rik; 68kDa; Taf2n; TAFII68
Species Mus musculus
Ensembl Gene ENSMUSG00000020680
Encoded Proteins
IDBP-205440
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor
IDBP-533535
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog null:
This gene encodes a member of the TET family of RNA-binding proteins. The encoded protein plays a role in RNA polymerase II gene transcription as a component of a distinct subset of multi-subunit transcription initiation factor TFIID complexes. Translocations involving this gene play a role in acute leukemia and extraskeletal myxoid chondrosarcoma, and mutations in this gene may play a role in amyotrophic lateral sclerosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:83473086-83506743
Strand Forward strand
Band C
Transcripts
ENSMUST00000021018 ENSMUSP00000021018
ENSMUST00000134185
ENSMUST00000152405
ENSMUST00000126134
ENSMUST00000133170 ENSMUSP00000119836
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 39 interaction(s) predicted by orthology.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 39 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
null
View Gene Order
ENSBTAG00000006916
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu03022
Basal transcription factors pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa03022
Basal transcription factors pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL Q8BQ46
UniProt Splice Variant
Entrez Gene 70439
UniGene
RefSeq NM_027427
OMIM
CCDS CCDS25168
HPRD
IMGT
MGI ID MGI:1917689
MGI Symbol Taf15
EMBL AK051568 AK146331 AL596122 AL663096 BC137591
GenPept AAI37592 BAC34676 BAE27086
RNA Seq Atlas 70439

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca