Version 5.4
Mus musculus Gene: Snx5
Summary
InnateDB Gene IDBG-208427.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Snx5
Gene Name sorting nexin 5
Synonyms 0910001N05Rik; 1810032P22Rik; AU019504; D2Ertd52e
Species Mus musculus
Ensembl Gene ENSMUSG00000027423
Encoded Proteins
IDBP-208429
sorting nexin 5
IDBP-261134
sorting nexin 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000089006:
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein binds to fanconi anemia complementation group A protein, but its function is unknown. This gene results in two transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:144250123-144270906
Strand Reverse strand
Band G1
Transcripts
ENSMUST00000028909 ENSMUSP00000028909
ENSMUST00000110030 ENSMUSP00000105657
ENSMUST00000138745
ENSMUST00000125285
ENSMUST00000156936
ENSMUST00000124389
ENSMUST00000153033
ENSMUST00000155509
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 18 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0035091 phosphatidylinositol binding
Biological Process
GO:0006886 intracellular protein transport
GO:0006907 pinocytosis
Cellular Component
GO:0001726 ruffle
GO:0001891 phagocytic cup
GO:0005768 endosome
GO:0030659 cytoplasmic vesicle membrane
GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
GO:0031313 extrinsic component of endosome membrane
GO:0031901 early endosome membrane
GO:0070685 macropinocytic cup
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000089006
View Gene Order
ENSBTAG00000003422
Not yet available
Pathways
NETPATH
REACTOME
REACT_209837
Membrane Trafficking pathway
REACT_232671
Golgi Associated Vesicle Biogenesis pathway
REACT_243409
trans-Golgi Network Vesicle Budding pathway
REACT_234979
Clathrin derived vesicle budding pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_4
EGFR1 pathway
REACTOME
REACT_19400
Golgi Associated Vesicle Biogenesis pathway
REACT_19187
Clathrin derived vesicle budding pathway
REACT_11235
trans-Golgi Network Vesicle Budding pathway
REACT_11123
Membrane Trafficking pathway
REACT_219531
Golgi Associated Vesicle Biogenesis pathway
REACT_216751
Clathrin derived vesicle budding pathway
REACT_211153
trans-Golgi Network Vesicle Budding pathway
REACT_213260
Membrane Trafficking pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.444953
RefSeq NM_001199188 NM_024225
OMIM
CCDS CCDS16815
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca