Version 5.4
Mus musculus Gene: Lpgat1
Summary
InnateDB Gene IDBG-208842.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lpgat1
Gene Name lysophosphatidylglycerol acyltransferase 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000026623
Encoded Proteins
IDBP-259360
lysophosphatidylglycerol acyltransferase 1
IDBP-259362
lysophosphatidylglycerol acyltransferase 1
IDBP-531914
lysophosphatidylglycerol acyltransferase 1
IDBP-538363
lysophosphatidylglycerol acyltransferase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000123684:
Acyl-CoA:lysophosphatidylglycerol (LPG) acyltransferase catalyzes the reacylation of LPG to phosphatidylglycerol, a membrane phospholipid that is an important precursor for the synthesis of cardiolipin (Yang et al., 2004 [PubMed 15485873]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:191717834-191784255
Strand Forward strand
Band H6
Transcripts
ENSMUST00000110856 ENSMUSP00000106480
ENSMUST00000110855 ENSMUSP00000106479
ENSMUST00000133076 ENSMUSP00000115255
ENSMUST00000138494
ENSMUST00000130876 ENSMUSP00000114382
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0016746 transferase activity, transferring acyl groups
Biological Process
GO:0008150 biological_process
GO:0008152 metabolic process
GO:0008654 phospholipid biosynthetic process
Cellular Component
GO:0005575 cellular_component
GO:0005737 cytoplasm
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000123684
View Gene Order
ENSBTAG00000005137
Not yet available
Pathways
NETPATH
REACTOME
REACT_199039
Acyl chain remodelling of PG pathway
REACT_188937
Metabolism pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
REACT_188641
Glycerophospholipid biosynthesis pathway
REACT_188643
Phospholipid metabolism pathway
KEGG
mmu00564
Glycerophospholipid metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_121324
Acyl chain remodelling of PG pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_121401
Glycerophospholipid biosynthesis pathway
REACT_120870
Phospholipid metabolism pathway
REACT_111217
Metabolism pathway
KEGG
hsa00564
Glycerophospholipid metabolism pathway
INOH
PID NCI
Cross-References
SwissProt Q91YX5
TrEMBL D3YVK0 Q8R1E1
UniProt Splice Variant
Entrez Gene 226856
UniGene Mm.277958 Mm.354677 Mm.394068 Mm.397684 Mm.423449 Mm.475770
RefSeq NM_172266 XM_006497155 XM_006497156 XM_006497157 NM_001134829 XM_006497153
OMIM
CCDS CCDS15622 CCDS48488
HPRD
IMGT
MGI ID MGI:2446186
MGI Symbol Lpgat1
EMBL AC157810 BC013667 BC024750
GenPept AAH13667 AAH24750
RNA Seq Atlas 226856

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca