Mus musculus Gene: Eif3c
Summary
InnateDB Gene IDBG-209573.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Eif3c
Gene Name eukaryotic translation initiation factor 3, subunit C
Synonyms 110kDa; 3230401O13Rik; Eif3s8; NIPIL(A3); NipilA3; Xs; Xsl;
Species Mus musculus
Ensembl Gene ENSMUSG00000030738
Encoded Proteins
eukaryotic translation initiation factor 3, subunit C
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000184110:
Gene Information
Type Protein coding
Genomic Location Chromosome 7:126546455-126566411
Strand Reverse strand
Band F3
Transcripts
ENSMUST00000032992 ENSMUSP00000032992
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 74 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 74 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003743 translation initiation factor activity
GO:0005515 protein binding
GO:0031369 translation initiation factor binding
Biological Process
GO:0001731 formation of translation preinitiation complex
GO:0006413 translational initiation
GO:0006446 regulation of translational initiation
Cellular Component
GO:0005852 eukaryotic translation initiation factor 3 complex
GO:0016282 eukaryotic 43S preinitiation complex
GO:0033290 eukaryotic 48S preinitiation complex
GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S pathway
Translation pathway
Translation initiation complex formation pathway
Metabolism of proteins pathway
Cap-dependent Translation Initiation pathway
Eukaryotic Translation Initiation pathway
Formation of a pool of free 40S subunits pathway
Gene Expression pathway
L13a-mediated translational silencing of Ceruloplasmin expression pathway
Ribosomal scanning and start codon recognition pathway
GTP hydrolysis and joining of the 60S ribosomal subunit pathway
Formation of the ternary complex, and subsequently, the 43S complex pathway
KEGG
RNA transport pathway
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Eukaryotic Translation Initiation pathway
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S pathway
Formation of a pool of free 40S subunits pathway
Translation pathway
Translation initiation complex formation pathway
Metabolism of proteins pathway
Cap-dependent Translation Initiation pathway
Ribosomal scanning and start codon recognition pathway
GTP hydrolysis and joining of the 60S ribosomal subunit pathway
Formation of the ternary complex, and subsequently, the 43S complex pathway
L13a-mediated translational silencing of Ceruloplasmin expression pathway
Gene Expression pathway
Formation of the ternary complex, and subsequently, the 43S complex pathway
L13a-mediated translational silencing of Ceruloplasmin expression pathway
Gene Expression pathway
Eukaryotic Translation Initiation pathway
Cap-dependent Translation Initiation pathway
Formation of a pool of free 40S subunits pathway
Translation pathway
GTP hydrolysis and joining of the 60S ribosomal subunit pathway
Metabolism of proteins pathway
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S pathway
Translation initiation complex formation pathway
Ribosomal scanning and start codon recognition pathway
KEGG
RNA transport pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt Q8R1B4
TrEMBL Q3TL08 Q66JU1 Q9CV26
UniProt Splice Variant
Entrez Gene 56347
UniGene Mm.22776 Mm.401564
RefSeq NM_146200
OMIM
CCDS CCDS21832
HPRD
IMGT
MGI ID MGI:1926966
MGI Symbol Eif3c
EMBL AK009925 AK160078 AK166743 BC024855 BC025032 BC080763
GenPept AAH24855 AAH25032 AAH80763 BAB26588 BAE35610 BAE38985
RNA Seq Atlas 56347