Version 5.4
Mus musculus Gene: Srcap
Summary
InnateDB Gene IDBG-210226.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Srcap
Gene Name Snf2-related CREBBP activator protein
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000053877
Encoded Proteins
IDBP-210228
Snf2-related CREBBP activator protein
IDBP-210230
Snf2-related CREBBP activator protein
IDBP-789455
Snf2-related CREBBP activator protein
IDBP-789456
Snf2-related CREBBP activator protein
IDBP-789457
Snf2-related CREBBP activator protein
IDBP-789462
Snf2-related CREBBP activator protein
IDBP-789466
Snf2-related CREBBP activator protein
IDBP-789468
Snf2-related CREBBP activator protein
IDBP-789472
Snf2-related CREBBP activator protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000080603:
This gene encodes the core catalytic component of the multiprotein chromatin-remodeling SRCAP complex. The encoded protein is an ATPase that is necessary for the incorporation of the histone variant H2A.Z into nucleosomes. It can function as a transcriptional activator in Notch-mediated, CREB-mediated and steroid receptor-mediated transcription. Mutations in this gene cause Floating-Harbor syndrome, a rare disorder characterized by short stature, language deficits and dysmorphic facial features. [provided by RefSeq, Feb 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:127511983-127567054
Strand Forward strand
Band F3
Transcripts
ENSMUST00000066582 ENSMUSP00000063817
ENSMUST00000098025 ENSMUSP00000095635
ENSMUST00000185401
ENSMUST00000188124 ENSMUSP00000140882
ENSMUST00000189136 ENSMUSP00000141098
ENSMUST00000187442
ENSMUST00000189449
ENSMUST00000186672 ENSMUSP00000140395
ENSMUST00000187164
ENSMUST00000187040 ENSMUSP00000140036
ENSMUST00000186759
ENSMUST00000190390 ENSMUSP00000139399
ENSMUST00000186954 ENSMUSP00000139536
ENSMUST00000189629 ENSMUSP00000139644
ENSMUST00000189812
ENSMUST00000190278
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.
Predicted by orthology
Total 25 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0004386 helicase activity
GO:0005524 ATP binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005634 nucleus
GO:0005794 Golgi apparatus
GO:0043234 protein complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000080603
View Gene Order
ENSBTAG00000013917
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 100043597
UniGene
RefSeq XM_006508422 XM_006508423 XM_006508424 XM_006508425 XM_006508426 XM_006508427 XM_006508428 XM_006508429 XM_006544271
OMIM
CCDS
HPRD
IMGT
MGI ID MGI:2444036
MGI Symbol Srcap
EMBL
GenPept
RNA Seq Atlas 100043597

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca