Version 5.4
Mus musculus Gene: Mpp3
Summary
InnateDB Gene IDBG-212414.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mpp3
Gene Name membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
Synonyms 6430514B01; Dlgh3
Species Mus musculus
Ensembl Gene ENSMUSG00000052373
Encoded Proteins
IDBP-212416
membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
IDBP-212418
membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
IDBP-267249
membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
IDBP-267251
membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000161647:
This gene product is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. This protein contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction. Alternatively spliced transcript variants have been identified. One transcript variant is experimentally supported, but it doesn't encode a protein. [provided by RefSeq, Jul 2008]
This gene product is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. This protein contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction. Alternatively spliced transcript variants have been identified. One transcript variant is experimentally supported, but it doesn\'t encode a protein. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:101999652-102028461
Strand Reverse strand
Band D
Transcripts
ENSMUST00000062801 ENSMUSP00000055469
ENSMUST00000100400 ENSMUSP00000097969
ENSMUST00000107168 ENSMUSP00000102786
ENSMUST00000107167 ENSMUSP00000102785
ENSMUST00000132094
ENSMUST00000127053
ENSMUST00000147838
ENSMUST00000155751
ENSMUST00000141403
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 31 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 31 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0016301 kinase activity
GO:0030165 PDZ domain binding
Biological Process
GO:0016310 phosphorylation
Cellular Component
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000161647
View Gene Order
ENSBTAG00000017536
Not yet available
Cross-References
SwissProt
TrEMBL Q6XE40
UniProt Splice Variant
Entrez Gene 13384
UniGene Mm.20449 Mm.408925
RefSeq NM_007863 XM_006532138 XM_006532140
OMIM
CCDS CCDS36338
HPRD
IMGT
MGI ID MGI:1328354
MGI Symbol Mpp3
EMBL AL591145 AY236514 BC062642
GenPept AAH62642 AAO65586
RNA Seq Atlas 13384

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca