Homo sapiens Gene: INS-IGF2
Summary
InnateDB Gene IDBG-21412.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol INS-IGF2
Gene Name INS-IGF2 readthrough
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000129965
Encoded Proteins
INS-IGF2 readthrough
INS-IGF2 readthrough
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This locus includes two alternatively spliced read-through transcript variants which align to the INS gene in the 5' region and to the IGF2 gene in the 3' region. One transcript is predicted to encode a protein which shares the N-terminus with the INS protein but has a distinct and longer C-terminus, whereas the other transcript is a candidate for nonsense-mediated decay (NMD). The transcripts are imprinted and are paternally expressed in the limb and eye. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:2132538-2161209
Strand Reverse strand
Band p15.5
Transcripts
ENST00000356578 ENSP00000348986
ENST00000397270 ENSP00000380440
ENST00000481781
ENST00000476874
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005179 hormone activity
Biological Process
Cellular Component
GO:0005576 extracellular region
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
INOH
PID BIOCARTA
Insulin signaling pathway [Biocarta view]
Growth hormone signaling pathway [Biocarta view]
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001042376
HUGO
OMIM
CCDS CCDS41598
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas