Mus musculus Gene: Alyref
Summary
InnateDB Gene IDBG-214845.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Alyref
Gene Name Aly/REF export factor
Synonyms ALY; REF1; Refbp1; Thoc4;
Species Mus musculus
Ensembl Gene ENSMUSG00000025134
Encoded Proteins
THO complex 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000183684:
The protein encoded by this gene is a heat stable, nuclear protein and functions as a molecular chaperone. It is thought to regulate dimerization, DNA binding, and transcriptional activity of basic region-leucine zipper (bZIP) proteins. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:120592121-120598365
Strand Reverse strand
Band E2
Transcripts
ENSMUST00000026125 ENSMUSP00000026125
ENSMUST00000155325
ENSMUST00000156685
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 70 interaction(s) predicted by orthology.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 70 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003697 single-stranded DNA binding
GO:0003723 RNA binding
Biological Process
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:0051028 mRNA transport
Cellular Component
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005737 cytoplasm
GO:0016607 nuclear speck
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
SSD Ortholog
Ortholog supports species divergence
Not yet available
SSD Ortholog
Ortholog supports species divergence
Pathways
NETPATH
REACTOME
mRNA 3'-end processing pathway
Transport of Mature Transcript to Cytoplasm pathway
mRNA Splicing pathway
RNA Polymerase II Transcription Termination pathway
Cleavage of Growing Transcript in the Termination Region pathway
Gene Expression pathway
Transport of the SLBP independent Mature mRNA pathway
mRNA Splicing - Major Pathway pathway
Transport of Mature mRNA Derived from an Intronless Transcript pathway
Transport of Mature mRNAs Derived from Intronless Transcripts pathway
Transport of Mature mRNA derived from an Intron-Containing Transcript pathway
Transport of the SLBP Dependant Mature mRNA pathway
Processing of Capped Intron-Containing Pre-mRNA pathway
RNA Polymerase II Transcription pathway
KEGG
RNA transport pathway
mRNA surveillance pathway pathway
Spliceosome pathway
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Transport of Mature mRNA derived from an Intron-Containing Transcript pathway
mRNA 3'-end processing pathway
RNA Polymerase II Transcription Termination pathway
Transport of Mature mRNA Derived from an Intronless Transcript pathway
Processing of Capped Intron-Containing Pre-mRNA pathway
Transport of the SLBP independent Mature mRNA pathway
RNA Polymerase II Transcription pathway
Transport of Mature Transcript to Cytoplasm pathway
Transport of Mature mRNAs Derived from Intronless Transcripts pathway
mRNA Splicing pathway
Cleavage of Growing Transcript in the Termination Region pathway
Transport of the SLBP Dependant Mature mRNA pathway
Gene Expression pathway
mRNA Splicing - Major Pathway pathway
RNA Polymerase II Transcription pathway
Cleavage of Growing Transcript in the Termination Region pathway
mRNA Splicing - Major Pathway pathway
mRNA Splicing pathway
mRNA 3'-end processing pathway
Transport of Mature Transcript to Cytoplasm pathway
RNA Polymerase II Transcription Termination pathway
Transport of Mature mRNA Derived from an Intronless Transcript pathway
Gene Expression pathway
Transport of Mature mRNA derived from an Intron-Containing Transcript pathway
Transport of the SLBP independent Mature mRNA pathway
Processing of Capped Intron-Containing Pre-mRNA pathway
Transport of the SLBP Dependant Mature mRNA pathway
Transport of Mature mRNAs Derived from Intronless Transcripts pathway
KEGG
RNA transport pathway
mRNA surveillance pathway pathway
Spliceosome pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.410517
RefSeq NM_011568
OMIM
CCDS CCDS25744
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas